TY - JOUR
T1 - Femoral version deformities alter joint reaction forces in dysplastic hips during gait
AU - Shepherd, Molly C.
AU - Gaffney, Brecca M.M.
AU - Song, Ke
AU - Clohisy, John C.
AU - Nepple, Jeffrey J.
AU - Harris, Michael D.
N1 - Funding Information:
This project was supported by the National Institutes of Health K01AR072072, P30AR074992, F32AR075349, T32HD007434, and the American Society of Biomechanics Junior Faculty Research Award. The research content herein is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This research was done using resources provided by the Open Science Grid (Pordes et al., 2007; Sfiligoi et al., 2009), which is supported by the National Science Foundation award #2030508.
Funding Information:
This project was supported by the National Institutes of Health K01AR072072, P30AR074992, F32AR075349, T32HD007434, and the American Society of Biomechanics Junior Faculty Research Award. The research content herein is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This research was done using resources provided by the Open Science Grid (Pordes et al. 2007; Sfiligoi et al. 2009), which is supported by the National Science Foundation award #2030508.
Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/4
Y1 - 2022/4
N2 - Developmental dysplasia of the hip (DDH) causes hip instability and early-onset osteoarthritis. The focus on pathomechanics in DDH has centered on the shallow acetabulum, however there is growing awareness of the role of femoral deformities in joint damage. The objective of this study was to determine the influence of femoral version (FV) on the muscle and joint reaction forces (JRFs) of dysplastic hips during gait. Magnetic resonance images, in-vivo gait data, and musculoskeletal models were used to calculate JRFs and simulate changes due to varying FV deformities. Rotation about the long axis of the femur was added in the musculoskeletal models to simulate FV values from −5° (relative retroversion) to + 35° (increased anteversion). In our simulations, FV deformities caused the largest changes to the anteroposterior and resultant JRFs. From a normal FV of 15°, a 15° increase in femoral anteversion caused JRFs to be less posterior in early stance (Δ = 0.43 ± 0.22 xbodyweight) and more anterior in late stance (Δ = 0.60 ± 14 xbodyweight). Relative retroversion caused anteroposterior changes that were similar to anteversion in early stance but opposite in late stance. Resultant JRFs experienced the largest changes during late stance where anteversion raised the peak by 0.48 ± 0.15 xbodyweight and relative retroversion lowered the peak by 0.32 ± 0.30 xbodyweight. Increasing anteversion increased hip flexor and abductor muscle forces, which caused the changes in JRFs. Identifying how FV deformities influence hip joint loading can elucidate their role in the mechanisms of hip degeneration in patients with DDH.
AB - Developmental dysplasia of the hip (DDH) causes hip instability and early-onset osteoarthritis. The focus on pathomechanics in DDH has centered on the shallow acetabulum, however there is growing awareness of the role of femoral deformities in joint damage. The objective of this study was to determine the influence of femoral version (FV) on the muscle and joint reaction forces (JRFs) of dysplastic hips during gait. Magnetic resonance images, in-vivo gait data, and musculoskeletal models were used to calculate JRFs and simulate changes due to varying FV deformities. Rotation about the long axis of the femur was added in the musculoskeletal models to simulate FV values from −5° (relative retroversion) to + 35° (increased anteversion). In our simulations, FV deformities caused the largest changes to the anteroposterior and resultant JRFs. From a normal FV of 15°, a 15° increase in femoral anteversion caused JRFs to be less posterior in early stance (Δ = 0.43 ± 0.22 xbodyweight) and more anterior in late stance (Δ = 0.60 ± 14 xbodyweight). Relative retroversion caused anteroposterior changes that were similar to anteversion in early stance but opposite in late stance. Resultant JRFs experienced the largest changes during late stance where anteversion raised the peak by 0.48 ± 0.15 xbodyweight and relative retroversion lowered the peak by 0.32 ± 0.30 xbodyweight. Increasing anteversion increased hip flexor and abductor muscle forces, which caused the changes in JRFs. Identifying how FV deformities influence hip joint loading can elucidate their role in the mechanisms of hip degeneration in patients with DDH.
KW - Developmental dysplasia of the hip
KW - Femoral version
KW - Gait
KW - Joint reaction forces
KW - Musculoskeletal modeling
UR - http://www.scopus.com/inward/record.url?scp=85125487627&partnerID=8YFLogxK
U2 - 10.1016/j.jbiomech.2022.111023
DO - 10.1016/j.jbiomech.2022.111023
M3 - Article
C2 - 35247684
AN - SCOPUS:85125487627
SN - 0021-9290
VL - 135
JO - Journal of Biomechanics
JF - Journal of Biomechanics
M1 - 111023
ER -