Febrile Seizures

R. A. Shellhaas, C. S. Camfield, P. R. Camfield

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


The basic facts about febrile seizures are clear - brain damage and death do not occur, subsequent epilepsy is rare (<3%), recurrences are common (30-40%), and parents are very upset. Buccal or nasal midazolam appears to be the most effective method to stop an ongoing febrile seizure. Although fever is a key ingredient, the only role for antipyretics is to make the child comfortable. They do not prevent or stop febrile seizures. There is still no clearly effective preventative strategy. The sequence of a prolonged febrile seizure leading to intractable temporal lobe epilepsy with mesial temporal sclerosis is rare. The disorder is complicated but a robust literature provides reasonable answers to most management issues.

Original languageEnglish
Title of host publicationEncyclopedia of the Neurological Sciences
PublisherElsevier Inc.
Number of pages2
ISBN (Electronic)9780123851574
ISBN (Print)9780123851581
StatePublished - Jan 1 2014


  • Acetaminophen
  • Antipyretics
  • Complex seizures
  • Epilepsy
  • Fever
  • Focal seizures
  • Genetic predisposition
  • Prolonged seizures
  • Recurrence
  • Risk factors
  • Status epilepticus


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