Fatty Acid Desaturation Gets a NAD+ Reputation

Andrew J. Lutkewitte; Shawn C. Burgess; Brian N. Finck

doi:10.1016/j.cmet.2019.03.007

Fatty Acid Desaturation Gets a NAD⁺ Reputation

Andrew J. Lutkewitte
, Shawn C. Burgess
, Brian N. Finck

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD⁺ by this desaturase reaction is an adaptive response to NAD⁺ depletion that may regulate cellular REDOX status.

Original language	English
Pages (from-to)	790-792
Number of pages	3
Journal	Cell metabolism
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2019.03.007
State	Published - Apr 2 2019

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title = "Fatty Acid Desaturation Gets a NAD+ Reputation",

abstract = "delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD+ by this desaturase reaction is an adaptive response to NAD+ depletion that may regulate cellular REDOX status.",

author = "Lutkewitte, \{Andrew J.\} and Burgess, \{Shawn C.\} and Finck, \{Brian N.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

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doi = "10.1016/j.cmet.2019.03.007",

language = "English",

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T1 - Fatty Acid Desaturation Gets a NAD+ Reputation

AU - Lutkewitte, Andrew J.

AU - Burgess, Shawn C.

AU - Finck, Brian N.

PY - 2019/4/2

Y1 - 2019/4/2

N2 - delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD+ by this desaturase reaction is an adaptive response to NAD+ depletion that may regulate cellular REDOX status.

AB - delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD+ by this desaturase reaction is an adaptive response to NAD+ depletion that may regulate cellular REDOX status.

UR - https://www.scopus.com/pages/publications/85063297298

U2 - 10.1016/j.cmet.2019.03.007

DO - 10.1016/j.cmet.2019.03.007

M3 - Short survey

C2 - 30943390

AN - SCOPUS:85063297298

SN - 1550-4131

VL - 29

SP - 790

EP - 792

JO - Cell metabolism

JF - Cell metabolism

IS - 4

ER -

Fatty Acid Desaturation Gets a NAD⁺ Reputation

Abstract

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