Fat/Dachsous family cadherins in cell and tissue organisation

Alexander D. Fulford; Helen McNeill

doi:10.1016/j.ceb.2019.10.006

Fat/Dachsous family cadherins in cell and tissue organisation

Alexander D. Fulford, Helen McNeill

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Precisely controlled organisation at the cellular and tissue level is crucial to establish and maintain complex organisms. The atypical cadherins Fat (Ft), Fat2 and Dachsous (Ds) contribute to this organisation by regulating growth and planar cell polarity. Here we describe the recent advances in understanding how these large cadherins coordinate these processes, and discuss additional progress extending their function in regulation of microtubules, migration and disease.

Original language	English
Pages (from-to)	96-103
Number of pages	8
Journal	Current Opinion in Cell Biology
Volume	62
DOIs	https://doi.org/10.1016/j.ceb.2019.10.006
State	Published - Feb 2020

Keywords

Dachsous
Fat
Hippo signalling
Planar cell polarity

Access to Document

10.1016/j.ceb.2019.10.006

Link to publication in Scopus

Fingerprint Dive into the research topics of 'Fat/Dachsous family cadherins in cell and tissue organisation'. Together they form a unique fingerprint.

Cite this

@article{834ede994f764c068e82e5019a51418d,

title = "Fat/Dachsous family cadherins in cell and tissue organisation",

abstract = "Precisely controlled organisation at the cellular and tissue level is crucial to establish and maintain complex organisms. The atypical cadherins Fat (Ft), Fat2 and Dachsous (Ds) contribute to this organisation by regulating growth and planar cell polarity. Here we describe the recent advances in understanding how these large cadherins coordinate these processes, and discuss additional progress extending their function in regulation of microtubules, migration and disease.",

keywords = "Dachsous, Fat, Hippo signalling, Planar cell polarity",

author = "Fulford, {Alexander D.} and Helen McNeill",

year = "2020",

month = feb,

doi = "10.1016/j.ceb.2019.10.006",

language = "English",

volume = "62",

pages = "96--103",

journal = "Current Opinion in Cell Biology",

issn = "0955-0674",

}

TY - JOUR

T1 - Fat/Dachsous family cadherins in cell and tissue organisation

AU - Fulford, Alexander D.

AU - McNeill, Helen

PY - 2020/2

Y1 - 2020/2

N2 - Precisely controlled organisation at the cellular and tissue level is crucial to establish and maintain complex organisms. The atypical cadherins Fat (Ft), Fat2 and Dachsous (Ds) contribute to this organisation by regulating growth and planar cell polarity. Here we describe the recent advances in understanding how these large cadherins coordinate these processes, and discuss additional progress extending their function in regulation of microtubules, migration and disease.

AB - Precisely controlled organisation at the cellular and tissue level is crucial to establish and maintain complex organisms. The atypical cadherins Fat (Ft), Fat2 and Dachsous (Ds) contribute to this organisation by regulating growth and planar cell polarity. Here we describe the recent advances in understanding how these large cadherins coordinate these processes, and discuss additional progress extending their function in regulation of microtubules, migration and disease.

KW - Dachsous

KW - Fat

KW - Hippo signalling

KW - Planar cell polarity

UR - http://www.scopus.com/inward/record.url?scp=85074893435&partnerID=8YFLogxK

U2 - 10.1016/j.ceb.2019.10.006

DO - 10.1016/j.ceb.2019.10.006

M3 - Review article

C2 - 31739265

AN - SCOPUS:85074893435

VL - 62

SP - 96

EP - 103

JO - Current Opinion in Cell Biology

JF - Current Opinion in Cell Biology

SN - 0955-0674

ER -