Abstract
Bupropion is an antidepressant that is currently used in the treatment of depression, attention deficit-hyperactive disorder, and bipolar diseases; as well as an aid in smoking cessation. Although its neurotoxicity and propensity to cause seizures are well described in the literature, bupropion has been suggested to be a more desirable antidepressant when compared to the tricyclic antidepressants due to its lack of cardiotoxicity. To date, there are limited reports with regard to cardiac toxicity. The authors present a 15-year-old boy who developed torsades de pointes and cardiac arrest as a result of a bupropion overdose. Other reports of potential cardiac toxicity related to bupropion are reviewed.
Original language | English |
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Pages (from-to) | 136-138 |
Number of pages | 3 |
Journal | Journal of Intensive Care Medicine |
Volume | 17 |
Issue number | 3 |
State | Published - Dec 1 2002 |
Keywords
- Bupropion
- Overdose
- Tricyclic antidepressants
- Ventricular fibrillation