@article{90ee0e17df0f4da38813bf99c6bd40d3,
title = "FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits",
abstract = "Using mouse and human tissue genome engineering, Bowers et al. show that a human variant in fatty acid synthase (FASN) provides a link between altered lipid metabolism, neurogenic stem/progenitor activity, and brain function.",
keywords = "cognition, disease modeling, genome editing, hippocampus, intellectual disability, learning, lipid metabolism, neural stem cell, neurogenesis, organoid",
author = "Megan Bowers and Tong Liang and Daniel Gonzalez-Bohorquez and Sara Zocher and Jaeger, {Baptiste N.} and Kovacs, {Werner J.} and Clemens R{\"o}hrl and Cramb, {Kaitlyn M.L.} and Jochen Winterer and Merit Kruse and Slavica Dimitrieva and Overall, {Rupert W.} and Thomas Wegleiter and Hossein Najmabadi and Semenkovich, {Clay F.} and Gerd Kempermann and Csaba F{\"o}ldy and Sebastian Jessberger",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = jul,
day = "2",
doi = "10.1016/j.stem.2020.04.002",
language = "English",
volume = "27",
pages = "98--109.e11",
journal = "Cell Stem Cell",
issn = "1934-5909",
number = "1",
}