Familial transmission of a serious disease-producing group a streptococcus clone: Case reports and review

M. A. Gamba; M. Martinelli; H. J. Schaad; R. A. Streuli; J. Dipersio; L. Matter; H. B. Ris; F. Marchal; E. L. Kaplan; D. L. Stevens; R. Malinverni

doi:10.1086/513636

Familial transmission of a serious disease-producing group a streptococcus clone: Case reports and review

M. A. Gamba, M. Martinelli, H. J. Schaad, R. A. Streuli, J. Dipersio, L. Matter, H. B. Ris, F. Marchal, E. L. Kaplan, D. L. Stevens, R. Malinverni

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Invasive group A streptococcus (GAS) infections are emerging diseases; however, person-to-person transmission of invasive GAS producing life- threatening infection has been observed rarely. We report a small intrafamilial cluster of life-threatening GAS infections. A previously healthy 47-year-old father developed necrotizing fasciitis of the neck. Two days later, his 16-year-old daughter developed streptococcal angina, pneumonia, and pleural empyema. Both patients had signs of streptococcal toxic shock syndrome. Pulsed field gel electrophoresis revealed that the M6 strains of GAS isolated from the father and daughter had identical patterns. Cases of person-to-person transmission of invasive GAS infection reported in the literature are also reviewed.

Original language	English
Pages (from-to)	1118-1121
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	24
Issue number	6
DOIs	https://doi.org/10.1086/513636
State	Published - 1997

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title = "Familial transmission of a serious disease-producing group a streptococcus clone: Case reports and review",

abstract = "Invasive group A streptococcus (GAS) infections are emerging diseases; however, person-to-person transmission of invasive GAS producing life- threatening infection has been observed rarely. We report a small intrafamilial cluster of life-threatening GAS infections. A previously healthy 47-year-old father developed necrotizing fasciitis of the neck. Two days later, his 16-year-old daughter developed streptococcal angina, pneumonia, and pleural empyema. Both patients had signs of streptococcal toxic shock syndrome. Pulsed field gel electrophoresis revealed that the M6 strains of GAS isolated from the father and daughter had identical patterns. Cases of person-to-person transmission of invasive GAS infection reported in the literature are also reviewed.",

author = "Gamba, {M. A.} and M. Martinelli and Schaad, {H. J.} and Streuli, {R. A.} and J. Dipersio and L. Matter and Ris, {H. B.} and F. Marchal and Kaplan, {E. L.} and Stevens, {D. L.} and R. Malinverni",

year = "1997",

doi = "10.1086/513636",

language = "English",

volume = "24",

pages = "1118--1121",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

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TY - JOUR

T1 - Familial transmission of a serious disease-producing group a streptococcus clone

T2 - Case reports and review

AU - Gamba, M. A.

AU - Martinelli, M.

AU - Schaad, H. J.

AU - Streuli, R. A.

AU - Dipersio, J.

AU - Matter, L.

AU - Ris, H. B.

AU - Marchal, F.

AU - Kaplan, E. L.

AU - Stevens, D. L.

AU - Malinverni, R.

PY - 1997

Y1 - 1997

N2 - Invasive group A streptococcus (GAS) infections are emerging diseases; however, person-to-person transmission of invasive GAS producing life- threatening infection has been observed rarely. We report a small intrafamilial cluster of life-threatening GAS infections. A previously healthy 47-year-old father developed necrotizing fasciitis of the neck. Two days later, his 16-year-old daughter developed streptococcal angina, pneumonia, and pleural empyema. Both patients had signs of streptococcal toxic shock syndrome. Pulsed field gel electrophoresis revealed that the M6 strains of GAS isolated from the father and daughter had identical patterns. Cases of person-to-person transmission of invasive GAS infection reported in the literature are also reviewed.

AB - Invasive group A streptococcus (GAS) infections are emerging diseases; however, person-to-person transmission of invasive GAS producing life- threatening infection has been observed rarely. We report a small intrafamilial cluster of life-threatening GAS infections. A previously healthy 47-year-old father developed necrotizing fasciitis of the neck. Two days later, his 16-year-old daughter developed streptococcal angina, pneumonia, and pleural empyema. Both patients had signs of streptococcal toxic shock syndrome. Pulsed field gel electrophoresis revealed that the M6 strains of GAS isolated from the father and daughter had identical patterns. Cases of person-to-person transmission of invasive GAS infection reported in the literature are also reviewed.

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U2 - 10.1086/513636

DO - 10.1086/513636

M3 - Review article

C2 - 9195067

AN - SCOPUS:0030949153

SN - 1058-4838

VL - 24

SP - 1118

EP - 1121

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 6

ER -

Familial transmission of a serious disease-producing group a streptococcus clone: Case reports and review

Abstract

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