Familial predisposition for otitis media in Apache Indians at Canyon Day, Arizona

N. Wendell Todd, D. C. Rao, C. Robert Cloninger

    Research output: Contribution to journalArticle

    12 Scopus citations

    Abstract

    The familial occurrence of otitis media was studied in White Mountain Apache Indians at Canyon Day, Arizona. Of the 760 residents, 366 persons were seen during a village survey for otitis media. There were 133 first‐degree relatives involving 113 first‐degree relative pairs. Of these, there were 38 children involving 19 separate sibling pairs, for whom age‐ and sex‐matched controls could be assigned. Tympanic membrane scarring was assumed to be a marker of prior otitis media. The findings suggested (P < .01 for the nonindependent first‐degree relative pairs, and P < .05 for the independent sibling pairs) a familial predisposition. With the additional assumption that the severity of tympanic membrane scarring can be ranked, no association of severity of otitis media was apparent in the first‐degree relatives.

    Original languageEnglish
    Pages (from-to)25-31
    Number of pages7
    JournalGenetic Epidemiology
    Volume4
    Issue number1
    DOIs
    StatePublished - 1987

    Keywords

    • North American Indians
    • familial aggregation
    • tympanic membrane

    Fingerprint Dive into the research topics of 'Familial predisposition for otitis media in Apache Indians at Canyon Day, Arizona'. Together they form a unique fingerprint.

  • Cite this