Abstract
Survival analysis of familial covariates of risk for affective illness demonstrated a significant effect on the proband's diagnosis when affection status included bipolar illness, but not major depressive disorder. A cohort effect was indicated only when broad spectra (including bipolar II and major depressive disorder) of illness were defined. Multifactorial analyses of familial correlations for affective illness evidenced neither sex‐specific correlations nor prevalences. We suggest the examination of risk variables prior to undertaking familial analysis.
Original language | English |
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Pages (from-to) | 241-246 |
Number of pages | 6 |
Journal | Genetic Epidemiology |
Volume | 6 |
Issue number | 1 |
DOIs | |
State | Published - 1989 |
Keywords
- affective disorder
- bipolar illness
- cohort effect
- multifactorial analysis
- survival analysis