False-positive pregnancy test secondary to ectopic expression of human chorionic gonadotropin by a gastrointestinal stromal tumor

Neal Andruska, Lily Mahapatra, Randall Brenneman, Kelly M. MacArthur, Peter Oppelt, Brian C. Baumann

Research output: Contribution to journalArticlepeer-review

Abstract

Tumors can rarely overexpress human chorionic gonadotropin (hCG) resulting in false-positive pregnancy tests. Here, we report a 44-year-old female with a metastatic gastrointestinal stromal tumor (GIST) who presented with a positive urine pregnancy test before radiotherapy. Further workup ruled out pregnancy. Following radiotherapy, her metastatic disease progressed and her hCG level continued to rise. To the best of our knowledge, this is the first report of a GIST tumor overexpressing hCG.

Original languageEnglish
Pages (from-to)809-812
Number of pages4
JournalJournal of surgical oncology
Volume122
Issue number4
DOIs
StatePublished - Sep 1 2020

Keywords

  • GIST
  • false-positive pregnancy test
  • gastrointestinal stromal tumor
  • hCG
  • human chorionic gonadotropin
  • sarcoma

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