Factors Influencing Reintervention Following Ductal Artery Stent Implantation for Ductal-Dependent Pulmonary Blood Flow: Results from the Congenital Cardiac Research Collaborative

Shabana Shahanavaz, Athar M. Qureshi, Christopher J. Petit, Bryan H. Goldstein, Andrew C. Glatz, Holly D. Bauser-Heaton, Courtney E. McCracken, Michael S. Kelleman, Mark A. Law, George T. Nicholson, Jeffrey D. Zampi, Joelle Pettus, Jeffery Meadows

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Background: Stenting of the patent ductus arteriosus (PDA) is an established palliative option for infants with ductal-dependent pulmonary blood flow. Following initial palliation, reintervention on the PDA stent is common, but risk factors have not been characterized. Methods: Infants with ductal-dependent pulmonary blood flow palliated with PDA stent between 2008 and 2015 were reviewed within the Congenital Cardiac Research Collaborative. Rates and risk factors for reintervention were analyzed. Results: Among 105 infants who underwent successful PDA stenting, 41 patients (39%) underwent a total of 53 reinterventions on the PDA stent, with all but one occurring within 6 months of the initial intervention. Stent redilation constituted the majority of reintervention (n=35; 66%) followed by additional stent placement (n=11; 21%) and surgical shunt placement (n=7; 13%). The majority of reintervention was nonurgent, and there were no deaths during the reintervention procedure. All but one reintervention occurred within 6 months of the initial procedure. On univariate analysis, risk factors for reintervention included anticipated single-ventricle physiology, lack of prior balloon pulmonary valvuloplasty, use of drug-eluting stent, and increased ductal tortuosity. Conclusions: In infants with ductal-dependent pulmonary blood flow palliated with PDA stent implantation, reintervention is common, can be performed safely, and is associated with both anatomic/procedural factors and anticipated final physiology.

Original languageEnglish
Pages (from-to)E010086
JournalCirculation: Cardiovascular Interventions
Volume14
Issue number12
DOIs
StatePublished - Dec 1 2021

Keywords

  • infant
  • pulmonary artery
  • risk factors
  • stents
  • tetralogy of Fallot

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