Factors associated with protective antibody levels to vaccine preventable diseases in internationally adopted children

Laura Patricia Stadler, Stephanie Donauer, Marilyn Rice, Indi Trehan, Shelia Salisbury, Mary Allen Staat

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

To determine which factors are predictive of protective antibody against vaccine-preventable diseases in internationally adopted children, we evaluated 562 children with serologic testing for at least one vaccine antigen before receiving a US vaccination. Vaccination status was defined as the number-of-doses recorded and as the presence of an up-to-date and valid record according to the American Academy of Pediatrics and the Advisory Committee on Immunization Practices guidelines. The number-of-doses recorded was the best predictor of protective antibody. These findings suggest that other options for immunization verification guidelines for internationally adopted children should be considered by policy makers.

Original languageEnglish
Pages (from-to)95-103
Number of pages9
JournalVaccine
Volume29
Issue number1
DOIs
StatePublished - Dec 10 2010

Keywords

  • Immunization
  • International adoption
  • Serology
  • Vaccine preventable diseases

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