Factores de riesgo de la enfermedad de Alzheimer

Cardiovascular risk factors were at the beginning more related to vascular dementia that to Alzheimer dementia (AD). However, during the last decades significant advances and researches have taken place and have increased the knowledge about Alzheimer disease. In addition, the last studies have found dissociation between the pathological brain findings and the symptoms of the AD. The limits between the cerebrovascular disease and the vascular dementia (DV) are difficult to define, many factors that are related to cerebrovascular disease and to the vascular dementia are related. Many cases of AD do have a simple pathogenesis. The post mortem studies on patients with AD and DV have shown the presence of cerebrovascular alterations in the firsts. And typical alterations of Alzheimer on the seconds. Also, that on both groups are shared common points such as elderly age and the vascular risk factors: High Blood Pressure (HBP), mellitus diabetes, obesity smoking addiction, hyperlipidemia, hyperhomocisteinemia y el haplotype E4 of Apolipoprotein E.