Abstract
Lordosis behavior was induced in previously unreceptive, ovariectomized estrogen-primed female guinea pigs by administration of the noradrenergic agonist clonidine. Clonidine also enhanced lordosis responding in females that were weakly receptive after estrogen priming. Unlike progesterone, the lordosis-facilitating effect of clonidine was not accompanied by a subsequent refractory period. Clonidine had a weak lordosis facilitatory effect when administered during the decline in receptivity to estrogen plus progesterone-primed animals and failed to induce lordosis when administered during the refractory period.
| Original language | English |
|---|---|
| Pages (from-to) | 207-209 |
| Number of pages | 3 |
| Journal | Pharmacology, Biochemistry and Behavior |
| Volume | 8 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1978 |
| Externally published | Yes |
Keywords
- Clonidine
- Estrogen
- Lordosis
- Progesterone
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Cite this
Crowley, W. R., Nock, B. L., & Feder, H. H. (1978). Facilitation of lordosis behavior by clonidine in female guinea pigs. Pharmacology, Biochemistry and Behavior, 8(2), 207-209. https://doi.org/10.1016/0091-3057(78)90339-8