TY - JOUR
T1 - Eye disease in kidney transplantation
T2 - Clinical challenges in a unique patient population
AU - Multani, Eisha K.
AU - Bajwa, Dalvir
AU - Multani, Priyanika K.
AU - Nobakht, Ehsan
AU - Raj, Dominic
AU - Paul, Rohan S.
N1 - Funding Information:
The authors would like to thank Dr. Carol Shields of Wills Eye Hospital, Philadelphia PA for providing clinical photographs.
Publisher Copyright:
© 2021 Elsevier Inc.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Eye disease is common among kidney transplant recipients, and their management is challenging. Chronic kidney disease is associated with ocular complications, both independently and in the context of various systemic disorders. In addition, chronic immunosuppression predisposes kidney transplant recipients to an array of long-term ocular issues. This may be broadly categorized into infections, malignancies, and other immunosuppression-specific side effects. The interdependence of kidney disease, transplant pharmacotherapy, and ocular health, therefore, requires a multispecialty approach. Although the kidney transplant population has grown along with the burden of associated oculopathies, systematic guidelines targeting this patient group are lacking. This evidenced-based narrative review summarizes the pertinent issues that may present in the ophthalmic and optometric clinical settings, with emphasis on collaborative management and directions for future research.
AB - Eye disease is common among kidney transplant recipients, and their management is challenging. Chronic kidney disease is associated with ocular complications, both independently and in the context of various systemic disorders. In addition, chronic immunosuppression predisposes kidney transplant recipients to an array of long-term ocular issues. This may be broadly categorized into infections, malignancies, and other immunosuppression-specific side effects. The interdependence of kidney disease, transplant pharmacotherapy, and ocular health, therefore, requires a multispecialty approach. Although the kidney transplant population has grown along with the burden of associated oculopathies, systematic guidelines targeting this patient group are lacking. This evidenced-based narrative review summarizes the pertinent issues that may present in the ophthalmic and optometric clinical settings, with emphasis on collaborative management and directions for future research.
KW - Chronic kidney disease
KW - Endstage renal disease
KW - Immunosuppression
KW - Kidney transplantation
KW - Opportunistic infection
KW - Solid organ transplantation
UR - http://www.scopus.com/inward/record.url?scp=85122945141&partnerID=8YFLogxK
U2 - 10.1016/j.survophthal.2021.12.007
DO - 10.1016/j.survophthal.2021.12.007
M3 - Review article
C2 - 34954092
AN - SCOPUS:85122945141
SN - 0039-6257
VL - 67
SP - 1252
EP - 1269
JO - Survey of ophthalmology
JF - Survey of ophthalmology
IS - 4
ER -