Extensive tumoral melanosis associated with ipilimumab-treated melanoma

K. Staser, D. Chen, J. Solus, I. S. Rosman, A. Schaffer, L. Cornelius, G. P. Linette, R. C. Fields

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Tumoral melanosis describes a pigmented lesion clinically similar to melanoma but on histology reveals dense aggregates of melanin-laden, benign macrophages without malignant cells. In the few reported cases so far, tumoral melanosis has arisen in the skin or lymph node of a patient with a regressed melanoma or an epithelioid tumour. As a marker of regressed primary melanoma, its discovery may prompt investigation and surveillance for undiagnosed local or metastatic disease. Here, we present a unique case of extensive tumoral melanosis arising during ipilimumab treatment of in-transit metastases from a previously excised melanoma.

Original languageEnglish
Pages (from-to)391-393
Number of pages3
JournalBritish Journal of Dermatology
Volume175
Issue number2
DOIs
StatePublished - Jan 1 2016

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