TY - JOUR
T1 - Extending supplementary feeding for children younger than 5 years with moderate acute malnutrition leads to lower relapse rates
AU - Trehan, Indi
AU - Banerjee, Somalee
AU - Murray, Ellen
AU - Ryan, Kelsey N.
AU - Thakwalakwa, Chrissie
AU - Maleta, Kenneth M.
AU - Manary, Mark J.
N1 - Publisher Copyright:
© Copyright 2015 by ESPGHAN and NASPGHAN. Unauthorized reproduction of this article is prohibited.
PY - 2015/4/9
Y1 - 2015/4/9
N2 - Objectives: Children with moderate acute malnutrition (MAM) have a high rate of relapse and death in the year following recovery. In this pilot study, we evaluate the long-term benefits of an extended course of nutritional therapy for children with MAM. Methods: Rural Malawian children 6 to 59 months old with MAM, defined as a weight-for-height z score (WHZ) between -2 and -3, were provided supplementary feeding for a fixed duration of 12 weeks. The children were then studied for 12 months to assess long-term nutritional status, and compared with children initially treated only until they first reached WHZ>-2. Results: Compared with children treated until they reached WHZ>-2, children treated for 12 weeks were more likely to remain well nourished (71% vs 63%, P=0.0015) and maintain more normal anthropometric indices during 12 months of follow-up; there was also a trend towards lower rates of severe acute malnutrition (7% vs 10%, P=0.067) and death (2% vs 4%, P=0.082). Regression modeling showed that mid-upper arm circumference and WHZ at the end of supplementary feeding were the most important factors in predicting which children remained well nourished (P<0.001 for each). Conclusions: The duration of supplementary feeding for children with MAM may not be as important as their anthropometry in terms of remaining well nourished after initial recovery. The presently accepted recovery criteria of WHZ of -2 may be insufficient for ensuring long-term nutritional health; consideration should be given to setting higher recovery criteria.
AB - Objectives: Children with moderate acute malnutrition (MAM) have a high rate of relapse and death in the year following recovery. In this pilot study, we evaluate the long-term benefits of an extended course of nutritional therapy for children with MAM. Methods: Rural Malawian children 6 to 59 months old with MAM, defined as a weight-for-height z score (WHZ) between -2 and -3, were provided supplementary feeding for a fixed duration of 12 weeks. The children were then studied for 12 months to assess long-term nutritional status, and compared with children initially treated only until they first reached WHZ>-2. Results: Compared with children treated until they reached WHZ>-2, children treated for 12 weeks were more likely to remain well nourished (71% vs 63%, P=0.0015) and maintain more normal anthropometric indices during 12 months of follow-up; there was also a trend towards lower rates of severe acute malnutrition (7% vs 10%, P=0.067) and death (2% vs 4%, P=0.082). Regression modeling showed that mid-upper arm circumference and WHZ at the end of supplementary feeding were the most important factors in predicting which children remained well nourished (P<0.001 for each). Conclusions: The duration of supplementary feeding for children with MAM may not be as important as their anthropometry in terms of remaining well nourished after initial recovery. The presently accepted recovery criteria of WHZ of -2 may be insufficient for ensuring long-term nutritional health; consideration should be given to setting higher recovery criteria.
KW - Malawi
KW - anthropometry
KW - children
KW - long-term outcomes
KW - mid-upper-arm circumference
KW - moderate acute malnutrition
KW - ready-to-use supplementary food
KW - wasting
KW - weight-for-height z score
UR - http://www.scopus.com/inward/record.url?scp=84927174032&partnerID=8YFLogxK
U2 - 10.1097/MPG.0000000000000639
DO - 10.1097/MPG.0000000000000639
M3 - Article
C2 - 25419681
AN - SCOPUS:84927174032
SN - 0277-2116
VL - 60
SP - 544
EP - 549
JO - Journal of pediatric gastroenterology and nutrition
JF - Journal of pediatric gastroenterology and nutrition
IS - 4
ER -