Expression of the Purkinje cell specific zebrin antigens in the cerebellum of the meander tail mutant mouse

Leonard M. Eisenman, John R. Pruett

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The cerebellum of the meander tail mutant mouse is characterized by normal cytoarchitecture in the posterior lobe and agranular, abnormal cytoarchitecture in the anterior lobe. The Purkinje cells form a monolayer in the posterior lobe but are dispersed throughout the cortex of the anterior lobe. Examination of these cells with the zebrin antibodies demonstrates that in spite of the morphologic and laminar disorganization of these cells in the anterior lobe, they are organized into the appropriate number of correctly positioned immunopositive zebrin clusters.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalBrain Research
Volume589
Issue number1
DOIs
StatePublished - Aug 28 1992
Externally publishedYes

Keywords

  • Genetics
  • Immunohistochemistry
  • Parasagittal organization

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