@article{65973110bcb14b46ba8d22f2363ff13a,
title = "Expression of antigen interaction structures on resting and activated cytotoxic lymphocytes",
abstract = "The expression of T-cell receptor protein and Lyt-2 was examined on resting and activated antigen-specific cytotoxic lymphocytes. Receptor expression was largely independent of the activation state of the cells. In contrast Lyt-2 expression was approximately threefold higher on activated than on resting cells. Since lytic activity varied by as much as 100-fold, it appears that lytic activity is primarily regulated by processes independent of quantitative changes in antigen interaction structures.",
author = "Russell, {John H.} and Patricia Meleedy-Rey and Susan Banes and Rawleigh Howe",
note = "Funding Information: {\textquoteright} This work wass upported by DHHSG rant CA34817. John H. Russell is the recipient of Research Career Development Award CA 00926 awarded by the National Cancer Institute, DHHS. Some materials were supplied by the Washington University Basic Cancer Research Center supported by Grant AI 15353. The Washington University FACS facility was initiated with the support of a grant from the Whittaker Foundation. * Abbreviations used: CTL, cytotoxic T lymphocyte; Hepes, 4-(2-hydroxyethyl)-l-piperazineethanesulfonic acid, IL2, interleukin 2; IUdR, 5-iodo2{\textquoteright}deoxyuridine; MHC, major histocompatibility complex; MLC, mixed-lymphocyte culture; MLC SN, supematants from secondary or tertiary mixed-lymphocyte cultures.",
year = "1986",
month = dec,
doi = "10.1016/0008-8749(86)90097-3",
language = "English",
volume = "103",
pages = "375--380",
journal = "Cellular Immunology",
issn = "0008-8749",
number = "2",
}