Expression of antigen interaction structures on resting and activated cytotoxic lymphocytes

John H. Russell, Patricia Meleedy-Rey, Susan Banes, Rawleigh Howe

Research output: Contribution to journalArticle

Abstract

The expression of T-cell receptor protein and Lyt-2 was examined on resting and activated antigen-specific cytotoxic lymphocytes. Receptor expression was largely independent of the activation state of the cells. In contrast Lyt-2 expression was approximately threefold higher on activated than on resting cells. Since lytic activity varied by as much as 100-fold, it appears that lytic activity is primarily regulated by processes independent of quantitative changes in antigen interaction structures.

Original languageEnglish
Pages (from-to)375-380
Number of pages6
JournalCellular Immunology
Volume103
Issue number2
DOIs
StatePublished - Dec 1986

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