Exercise-induced autophagy in fatty liver disease

Sung Kook Chun, Sooyeon Lee, Ming Jim Yang, Christiaan Leeuwenburgh, Jae Sung Kim

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Hepatic steatosis prevails each year. Autophagy is integral in mitochondrial quality control and lipid homeostasis in the liver. No pharmacological strategies are currently available to reduce hepatic steatosis, but exercise has been known to improve clinical outcomes of chronic liver disease, particularly nonalcoholic fatty liver disease (NAFLD). Recent studies suggest that exercise may improve NAFLD through enhancing autophagy.

Original languageEnglish
Pages (from-to)181-186
Number of pages6
JournalExercise and Sport Sciences Reviews
Volume45
Issue number3
DOIs
StatePublished - Jul 1 2017

Keywords

  • autophagy
  • exercise
  • lipids
  • liver
  • mitochondria
  • mitophagy
  • nonalcoholic fatty liver disease

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