Exercise-induced autophagy in fatty liver disease

Sung Kook Chun; Sooyeon Lee; Ming Jim Yang; Christiaan Leeuwenburgh; Jae Sung Kim

doi:10.1249/JES.0000000000000116

Exercise-induced autophagy in fatty liver disease

Sung Kook Chun, Sooyeon Lee, Ming Jim Yang, Christiaan Leeuwenburgh, Jae Sung Kim

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Hepatic steatosis prevails each year. Autophagy is integral in mitochondrial quality control and lipid homeostasis in the liver. No pharmacological strategies are currently available to reduce hepatic steatosis, but exercise has been known to improve clinical outcomes of chronic liver disease, particularly nonalcoholic fatty liver disease (NAFLD). Recent studies suggest that exercise may improve NAFLD through enhancing autophagy.

Original language	English
Pages (from-to)	181-186
Number of pages	6
Journal	Exercise and Sport Sciences Reviews
Volume	45
Issue number	3
DOIs	https://doi.org/10.1249/JES.0000000000000116
State	Published - Jul 1 2017

Keywords

autophagy
exercise
lipids
liver
mitochondria
mitophagy
nonalcoholic fatty liver disease

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10.1249/JES.0000000000000116

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title = "Exercise-induced autophagy in fatty liver disease",

abstract = "Hepatic steatosis prevails each year. Autophagy is integral in mitochondrial quality control and lipid homeostasis in the liver. No pharmacological strategies are currently available to reduce hepatic steatosis, but exercise has been known to improve clinical outcomes of chronic liver disease, particularly nonalcoholic fatty liver disease (NAFLD). Recent studies suggest that exercise may improve NAFLD through enhancing autophagy.",

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KW - exercise

KW - lipids

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KW - mitochondria

KW - mitophagy

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Exercise-induced autophagy in fatty liver disease

Abstract

Keywords

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