Executive response monitoring and inhibitory control in children with phenylketonuria: Effects of expectancy

Gabriel C. Araujo; Shawn E. Christ; Dorothy K. Grange; Robert D. Steiner; Carla Coleman; Evonne Timmerman; Desirée A. White

doi:10.1080/87565641.2012.718816

Executive response monitoring and inhibitory control in children with phenylketonuria: Effects of expectancy

Gabriel C. Araujo, Shawn E. Christ, Dorothy K. Grange, Robert D. Steiner, Carla Coleman, Evonne Timmerman, Desirée A. White

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Abstract

Response monitoring (post-error slowing) and inhibitory control (commission errors) were examined in children with phenylketonuria (PKU) and controls (6-18 years) using Go/No-Go tasks with higher (PKU n = 37; control n = 55) versus lower (PKU n = 24; control n = 25) non-target expectancy. On both tasks children with PKU exhibited impaired monitoring and inhibitory control, but the post-error slowing pattern was different. With higher expectancy children with PKU slowed more (less efficient monitoring) and with lower expectancy slowed less (less monitoring) than controls. No effects of age or phenylalanine level were noted. These results indicate that expectancy differentially effects monitoring and inhibitory control in PKU.

Original language	English
Pages (from-to)	139-152
Number of pages	14
Journal	Developmental Neuropsychology
Volume	38
Issue number	3
DOIs	https://doi.org/10.1080/87565641.2012.718816
State	Published - Apr 1 2013

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title = "Executive response monitoring and inhibitory control in children with phenylketonuria: Effects of expectancy",

abstract = "Response monitoring (post-error slowing) and inhibitory control (commission errors) were examined in children with phenylketonuria (PKU) and controls (6-18 years) using Go/No-Go tasks with higher (PKU n = 37; control n = 55) versus lower (PKU n = 24; control n = 25) non-target expectancy. On both tasks children with PKU exhibited impaired monitoring and inhibitory control, but the post-error slowing pattern was different. With higher expectancy children with PKU slowed more (less efficient monitoring) and with lower expectancy slowed less (less monitoring) than controls. No effects of age or phenylalanine level were noted. These results indicate that expectancy differentially effects monitoring and inhibitory control in PKU.",

author = "Araujo, {Gabriel C.} and Christ, {Shawn E.} and Grange, {Dorothy K.} and Steiner, {Robert D.} and Carla Coleman and Evonne Timmerman and White, {Desir{\'e}e A.}",

note = "Funding Information: This research was supported by the National Institute of Child Health and Human Development grant R01HD044901 and by the National Institute of General Medical Sciences grant T32GM081739. Correspondence should be addressed to Desir{\'e}e A. White, Ph.D., Department of Psychology, Washington University, Campus Box 1125, St. Louis, MO 63130. E-mail: dawhite@wustl.edu",

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AU - Araujo, Gabriel C.

AU - Christ, Shawn E.

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AU - Steiner, Robert D.

AU - Coleman, Carla

AU - Timmerman, Evonne

AU - White, Desirée A.

N1 - Funding Information: This research was supported by the National Institute of Child Health and Human Development grant R01HD044901 and by the National Institute of General Medical Sciences grant T32GM081739. Correspondence should be addressed to Desirée A. White, Ph.D., Department of Psychology, Washington University, Campus Box 1125, St. Louis, MO 63130. E-mail: dawhite@wustl.edu

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Y1 - 2013/4/1

N2 - Response monitoring (post-error slowing) and inhibitory control (commission errors) were examined in children with phenylketonuria (PKU) and controls (6-18 years) using Go/No-Go tasks with higher (PKU n = 37; control n = 55) versus lower (PKU n = 24; control n = 25) non-target expectancy. On both tasks children with PKU exhibited impaired monitoring and inhibitory control, but the post-error slowing pattern was different. With higher expectancy children with PKU slowed more (less efficient monitoring) and with lower expectancy slowed less (less monitoring) than controls. No effects of age or phenylalanine level were noted. These results indicate that expectancy differentially effects monitoring and inhibitory control in PKU.

AB - Response monitoring (post-error slowing) and inhibitory control (commission errors) were examined in children with phenylketonuria (PKU) and controls (6-18 years) using Go/No-Go tasks with higher (PKU n = 37; control n = 55) versus lower (PKU n = 24; control n = 25) non-target expectancy. On both tasks children with PKU exhibited impaired monitoring and inhibitory control, but the post-error slowing pattern was different. With higher expectancy children with PKU slowed more (less efficient monitoring) and with lower expectancy slowed less (less monitoring) than controls. No effects of age or phenylalanine level were noted. These results indicate that expectancy differentially effects monitoring and inhibitory control in PKU.

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Executive response monitoring and inhibitory control in children with phenylketonuria: Effects of expectancy

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