@article{483466d9734049f88406dcb3ded1a0f5,
title = "Examining the factor structure and discriminative utility of the Infant Behavior Questionnaire–Revised in infant siblings of autistic children",
abstract = "Using the Infant Behavior Questionnaire–Revised in a longitudinal sample of infant siblings of autistic children (HR; n = 427, 171 female, 83.4% White) and a comparison group of low-risk controls (LR, n = 200, 86 female, 81.5% White), collected between 2007 and 2017, this study identified an invariant factor structure of temperament traits across groups at 6 and 12 months. Second, after partitioning the groups by familial risk and diagnostic outcome at 24 months, results reveal an endophenotypic pattern of Positive Emotionality at both 6 and 12 months, (HR-autism spectrum disorder [ASD] < HR-no-ASD < LR). Third, increased {\textquoteleft}Duration of Orienting{\textquoteright} at 12 months was associated with lower scores on the 24-month developmental outcomes in HR infants. These findings may augment efforts for early identification of ASD.",
author = "{for the IBIS Network} and Sooyeon Sung and Angela Fenoglio and Wolff, {Jason J.} and Schultz, {Robert T.} and Botteron, {Kelly N.} and Dager, {Stephen R.} and Estes, {Annette M.} and Hazlett, {Heather C.} and Lonnie Zwaigenbaum and Joseph Piven and Elison, {Jed T.} and J. Piven and Hazlett, {H. C.} and C. Chappell and S. Dager and A. Estes and D. Shaw and K. Botteron and R. McKinstry and J. Constantino and J. Pruett and R. Schultz and J. Pandey and Elison, {J. T.} and Wolff, {J. J.} and Evans, {A. C.} and Collins, {D. L.} and Pike, {G. B.} and V. Fonov and P. Kostopoulos and S. Das and L. MacIntyre and G. Gerig and M. Styner and H. Gu",
note = "Funding Information: We thank the families who contributed their time and effort to the IBIS study. This work was supported by an NIH Autism Centers of Excellence Network grant R01 HD055741 (Piven), a grant from Autism Speaks #6020 (Piven), a grant from the Simons Foundation #140209 (Piven), and U54 Intellectual and Developmental Disabilities Research Centers (IDDRC) at each clinical site (HD079124 to UNC, Piven; HD087011 to Washington University, Constantino & Schlaggar; HD86984 to CHOP, Yudkoff; HD083091 to University of Washington, Guralnick). J. Elison is supported by R01 MH104324 and J. Wolff is supported by R01 MH116961. The Infant Brain Imaging Study (IBIS) Network is an NIH funded Autism Centers of Excellence project and consists of a consortium of 9 universities in the U.S. and Canada. Clinical Sites: University of North Carolina: J. Piven (IBIS Network PI), H. C. Hazlett, C. Chappell; University of Washington: S. Dager, A. Estes, D. Shaw; Washington University: K. Botteron, R. McKinstry, J. Constantino, J. Pruett: Children{\textquoteright}s Hospital of Philadelphia: R. Schultz, J. Pandey: University of Alberta: L. Zwaigenbaum: University of Minnesota; J. T. Elison, J. Wolff. Data Coordinating Center: Montreal Neurological Institute: A. C. Evans, D. L. Collins, G. B. Pike, V. Fonov, P. Kostopoulos, S. Das, L. MacIntyre. Image Processing Core: New York University: G. Gerig: University of North Carolina: M. Styner. Statistical Analysis Core: University of North Carolina: H. Gu. Funding Information: We thank the families who contributed their time and effort to the IBIS study. This work was supported by an NIH Autism Centers of Excellence Network grant R01 HD055741 (Piven), a grant from Autism Speaks #6020 (Piven), a grant from the Simons Foundation #140209 (Piven), and U54 Intellectual and Developmental Disabilities Research Centers (IDDRC) at each clinical site (HD079124 to UNC, Piven; HD087011 to Washington University, Constantino & Schlaggar; HD86984 to CHOP, Yudkoff; HD083091 to University of Washington, Guralnick). J. Elison is supported by R01 MH104324 and J. Wolff is supported by R01 MH116961. The Infant Brain Imaging Study (IBIS) Network is an NIH funded Autism Centers of Excellence project and consists of a consortium of 9 universities in the U.S. and Canada. Clinical Sites: University of North Carolina: J. Piven (IBIS Network PI), H. C. Hazlett, C. Chappell; University of Washington: S. Dager, A. Estes, D. Shaw; Washington University: K. Botteron, R. McKinstry, J. Constantino, J. Pruett: Children{\textquoteright}s Hospital of Philadelphia: R. Schultz, J. Pandey: University of Alberta: L. Zwaigenbaum: University of Minnesota; J. T. Elison, J. Wolff. Data Coordinating Center: Montreal Neurological Institute: A. C. Evans, D. L. Collins, G. B. Pike, V. Fonov, P. Kostopoulos, S. Das, L. MacIntyre. Image Processing Core: New York University: G. Gerig: University of North Carolina: M. Styner. Statistical Analysis Core: University of North Carolina: H. Gu. Publisher Copyright: {\textcopyright} 2022 The Authors. Child Development published by Wiley Periodicals LLC on behalf of Society for Research in Child Development.",
year = "2022",
month = sep,
day = "1",
doi = "10.1111/cdev.13781",
language = "English",
volume = "93",
pages = "1398--1413",
journal = "Child Development",
issn = "0009-3920",
number = "5",
}