Ex vivo Imaging of Human Pathologies with Integrated Optical Coherence Tomography (OCT) and Optical Coherence Microscopy (OCM)

Chao Zhou, Aaron D. Zhou, Yihong Wang, Bradley Bryan, Tsung Han Tsai, James L. Connolly, James G. Fujimoto

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations

Abstract

We report an imaging study using integrated 3D-OCT and OCM for the assessment of various human thyroid and breast pathologies. The 3D-OCT data sets enable en face projection imaging, which provides large field of view with uniform focus and signal level, while OCM provides high magnification that enables cellular resolution imaging. We have demonstrated that the integrated 3D-OCT and OCM technology provide a substantial improvement over standard OCT for the visualization of tissue pathology and can serve as a useful imaging tool in the clinical settings.

Original languageEnglish
Article number71680N
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7168
DOIs
StatePublished - 2009
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII - San Jose, CA, United States
Duration: Jan 26 2009Jan 28 2009

Keywords

  • Breast Cancer
  • Human Pathology
  • Optical Coherence Microscopy
  • Optical Coherence Tomography
  • Thyroid Cancer

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