TY - JOUR
T1 - Evolving disease resistance genes
AU - Meyers, Blake C.
AU - Kaushik, Shail
AU - Nandety, Raja Sekhar
N1 - Funding Information:
We are grateful to Kan Nobuta and John McDowell for helpful comments on the manuscript. Funding from the University of Delaware Research Foundation (UDRF) and a National Institute of Health (NIH) Centers of Biomedical Research Excellence (COBRE) award (P20 RR015588) supports research on disease resistance in the Meyers laboratory.
PY - 2005/4
Y1 - 2005/4
N2 - Defenses against most specialized plant pathogens are often initiated by a plant disease resistance gene. Plant genomes encode several classes of genes that can function as resistance genes. Many of the mechanisms that drive the molecular evolution of these genes are now becoming clear. The processes that contribute to the diversity of R genes include tandem and segmental gene duplications, recombination, unequal crossing-over, point mutations, and diversifying selection. Diversity within populations is maintained by balancing selection. Analyses of whole-genome sequences have and will continue to provide new insight into the dynamics of resistance gene evolution.
AB - Defenses against most specialized plant pathogens are often initiated by a plant disease resistance gene. Plant genomes encode several classes of genes that can function as resistance genes. Many of the mechanisms that drive the molecular evolution of these genes are now becoming clear. The processes that contribute to the diversity of R genes include tandem and segmental gene duplications, recombination, unequal crossing-over, point mutations, and diversifying selection. Diversity within populations is maintained by balancing selection. Analyses of whole-genome sequences have and will continue to provide new insight into the dynamics of resistance gene evolution.
UR - https://www.scopus.com/pages/publications/14744271279
U2 - 10.1016/j.pbi.2005.01.002
DO - 10.1016/j.pbi.2005.01.002
M3 - Review article
C2 - 15752991
AN - SCOPUS:14744271279
SN - 1369-5266
VL - 8
SP - 129
EP - 134
JO - Current Opinion in Plant Biology
JF - Current Opinion in Plant Biology
IS - 2
ER -