Abstract
Human brain evolution has involved reorganization of neural structure sizes, the distribution of cell types, axonal innervation patterns, and the expression of molecules and proteins. Microstructural specializations are evident with increased neuropil in the prefrontal cortex, modifications of neuromodulatory innervation of the neocortex and basal ganglia, and greater proportions of energetically costly long-range corticocortical projecting neurons. Some microstructural asymmetries in cortical regions associated with language and handedness might also be evolutionarily unique in the human brain.
Original language | English |
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Title of host publication | Evolution of Nervous Systems |
Subtitle of host publication | Second Edition |
Publisher | Elsevier Inc. |
Pages | 121-139 |
Number of pages | 19 |
Volume | 4-4 |
ISBN (Electronic) | 9780128040423 |
ISBN (Print) | 9780128040966 |
DOIs | |
State | Published - Jan 1 2016 |
Keywords
- Chimpanzee
- Glia
- Gorilla
- Histology
- Human brain evolution
- Interneuron
- Microstructure
- Neocortex
- Neuromodulator
- Neuropil
- Orangutan
- Pyramidal neuron