EVALUATION OF THE USE OF SIEVES FOR PRODUCING ESTIMATES OF RADIOACTIVITY DISTRIBUTIONS WITH THE EM ALGORITHM FOR PET.

Michael I. Miller, Donald L. Snyder, Stephen M. Moore

Research output: Contribution to journalArticlepeer-review

Abstract

Reconstructions of the spatial distributions of radio activity produced using maximum-likelihood estimation in positron emission tomography exhibit noise-like artifacts in the form of sharp peaks and valleys located randomly throughout the image field. These become increasingly apparent with each stage of iteration when the expectation-maximization algorithm is used to produce the maximum-likelihood estimate numerically. A preliminary evaluation of the use of Grenander's method of sieves to reduce these undesirable artifacts is presented.

Original languageEnglish
JournalIEEE Transactions on Nuclear Science
VolumeNS-33
Issue number1
StatePublished - Feb 1 1985

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