Evaluation of the inverse dynamic model in cerebellum during visual-vestibular interactions at different VOR gains in squirrel monkeys

Yutaka Hirata; Akimasa Yoshikawa; Pablo M. Blazquez; Stephen M. Highstein

doi:10.1016/j.neucom.2004.10.101

Evaluation of the inverse dynamic model in cerebellum during visual-vestibular interactions at different VOR gains in squirrel monkeys

Yutaka Hirata, Akimasa Yoshikawa, Pablo M. Blazquez, Stephen M. Highstein

Department of Otolaryngology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Generality of the cerebellar inverse dynamic model (IDM) theory was evaluated in oculomotor control in squirrel monkeys. Flocculus Purkinje cell firing patterns recorded during visual, vestibular, and their interaction paradigms at various vestibuloocular reflex (VOR) gains were reconstructed by the IDM consisting of the linear combination of eye position, velocity, and acceleration. The IDM could successfully reconstruct more than 72% of the firing patterns of 138 cells, but with different sets of parameters for different paradigms and different VOR gains. This result suggests that the output of the flocculus relates to motor output, but not the motor command per se.

Original language	English
Pages (from-to)	709-717
Number of pages	9
Journal	Neurocomputing
Volume	65-66
Issue number	SPEC. ISS.
DOIs	https://doi.org/10.1016/j.neucom.2004.10.101
State	Published - Jun 2005

Keywords

Cerebellum
Inverse dynamic model
Monkey
Motor learning
Purkinje cell
VOR

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10.1016/j.neucom.2004.10.101

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title = "Evaluation of the inverse dynamic model in cerebellum during visual-vestibular interactions at different VOR gains in squirrel monkeys",

abstract = "Generality of the cerebellar inverse dynamic model (IDM) theory was evaluated in oculomotor control in squirrel monkeys. Flocculus Purkinje cell firing patterns recorded during visual, vestibular, and their interaction paradigms at various vestibuloocular reflex (VOR) gains were reconstructed by the IDM consisting of the linear combination of eye position, velocity, and acceleration. The IDM could successfully reconstruct more than 72% of the firing patterns of 138 cells, but with different sets of parameters for different paradigms and different VOR gains. This result suggests that the output of the flocculus relates to motor output, but not the motor command per se.",

keywords = "Cerebellum, Inverse dynamic model, Monkey, Motor learning, Purkinje cell, VOR",

author = "Yutaka Hirata and Akimasa Yoshikawa and Blazquez, {Pablo M.} and Highstein, {Stephen M.}",

note = "Funding Information: Supported by a grant from the High-Tech Research Center Establishment Project from the Ministry of Education, Culture, Sports, Science and Technology, the “Ground-based Research Announcement for Space Utilization” promoted by the Japan Space Forum, and NIH EYE grant EY-05433. ",

year = "2005",

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doi = "10.1016/j.neucom.2004.10.101",

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AU - Hirata, Yutaka

AU - Yoshikawa, Akimasa

AU - Blazquez, Pablo M.

AU - Highstein, Stephen M.

N1 - Funding Information: Supported by a grant from the High-Tech Research Center Establishment Project from the Ministry of Education, Culture, Sports, Science and Technology, the “Ground-based Research Announcement for Space Utilization” promoted by the Japan Space Forum, and NIH EYE grant EY-05433.

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N2 - Generality of the cerebellar inverse dynamic model (IDM) theory was evaluated in oculomotor control in squirrel monkeys. Flocculus Purkinje cell firing patterns recorded during visual, vestibular, and their interaction paradigms at various vestibuloocular reflex (VOR) gains were reconstructed by the IDM consisting of the linear combination of eye position, velocity, and acceleration. The IDM could successfully reconstruct more than 72% of the firing patterns of 138 cells, but with different sets of parameters for different paradigms and different VOR gains. This result suggests that the output of the flocculus relates to motor output, but not the motor command per se.

AB - Generality of the cerebellar inverse dynamic model (IDM) theory was evaluated in oculomotor control in squirrel monkeys. Flocculus Purkinje cell firing patterns recorded during visual, vestibular, and their interaction paradigms at various vestibuloocular reflex (VOR) gains were reconstructed by the IDM consisting of the linear combination of eye position, velocity, and acceleration. The IDM could successfully reconstruct more than 72% of the firing patterns of 138 cells, but with different sets of parameters for different paradigms and different VOR gains. This result suggests that the output of the flocculus relates to motor output, but not the motor command per se.

KW - Cerebellum

KW - Inverse dynamic model

KW - Monkey

KW - Motor learning

KW - Purkinje cell

KW - VOR

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Evaluation of the inverse dynamic model in cerebellum during visual-vestibular interactions at different VOR gains in squirrel monkeys

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Keywords

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