Evaluation of linkage of the human C3b/C4b receptor to HLA

J. A. Hatch, J. P. Atkinson, B. K. Suarez, T. R. Dykman

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Abstract

Previous studies have suggested that genes controlling complement receptor expression are linked to the human leukocyte antigen (HLA) region. To determine whether the locus controlling C3bR polymorphism is linked to the HLA region, we have examined the inheritance of C3bR phenotypes in relationship to HLA. Our results indicate that the gene controlling C3bR phenotype is not closely linked to the HLA region. The implications of these findings are discussed in the view of the previous literature and recent developments in the study of complement receptors.

Original languageEnglish
Pages (from-to)2168-2169
Number of pages2
JournalJournal of Immunology
Volume132
Issue number5
StatePublished - 1984

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    Hatch, J. A., Atkinson, J. P., Suarez, B. K., & Dykman, T. R. (1984). Evaluation of linkage of the human C3b/C4b receptor to HLA. Journal of Immunology, 132(5), 2168-2169.