Evaluation of cardiolipin nanodisks as lipid replacement therapy for Barth syndrome

Keyphrases

• Cardiolipin 100%
• Barth Syndrome 100%
• Nanodiscs 100%
• Lipid Replacement Therapy 100%
• Knock-in Mouse Model 20%
• SiRNA Knockdown 10%
• Doxycycline-inducible 10%
• Cardiomyopathy 10%
• Cultured Cells 10%
• Phospholipids 10%
• In Vivo Applications 10%
• Effective Means 10%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 10%
• Mitochondrial Disease 10%
• Tafazzin 10%
• Transacylase 10%
• WT Mice 10%
• Skeletal muscle Weakness 10%
• Therapy Options 10%
• Extracted Lipid 10%
• Tafazzin Gene 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Replacement Therapy 100%
• Cardiolipin 100%
• Barth Syndrome 100%
• Nanodisc 100%
• Wild Type Mouse 10%
• Short Hairpin RNA 10%
• Doxycycline 10%
• Phospholipid 10%
• Acyltransferase 10%
• Muscle Weakness 10%
• Disorders of Mitochondrial Functions 10%
• Myocardial Disease 10%
• Diseases 10%

Biochemistry, Genetics and Molecular Biology

• Lipid 100%
• Cardiolipin 100%
• Tafazzin 20%
• Skeletal Muscle 10%
• Wild Type Mouse 10%
• N-Acetyltransferase 10%
• Liquid Chromatography-Mass Spectrometry 10%
• Small Hairpin RNA 10%
• Mitochondrial Disorder 10%
• Phospholipid 10%