CALCIUM ION (Ca++) has been administered as an insulin (IN) secretagogue in doses ranging from 4 to 5 mg/kg/hr over two to five hours in patients with insulinoma (1-4). Some reports (1,2) have indicated a significant increase in plasma IN during the CA++ infusion, while others (3,4) have demonstrated no change. We have previously observed, in patients with medullary thyroid carcinoma, that plasma calcitonin levels increased to higher peak levels more quickly following a rapid calcium infusion (RCI) than following a long calcium infusion (LCI). In the present study, fasting and stimulated plasma IN levels were compared in normal controls and in patients with insulinoma administered these two tests.
|Number of pages||4|
|State||Published - Jan 1 1984|