Evaluation of Antihistamine Drugs by Human [¹¹C]doxepin Dynamic PET Studies with a Parametric Image Approach

Keyphrases

• PET Study 100%
• Antihistamines 100%
• Dynamic PET 100%
• Doxepin 100%
• Parametric Image 100%
• H1 Receptor 100%
• Volume of Distribution 80%
• Cortex 40%
• Brain Tissue 40%
• Binding Potential 40%
• Spatial Constraints 40%
• Cetirizine 40%
• Fexofenadine 40%
• Diphenhydramine 40%
• Constraint Algorithm 40%
• Central Nervous System 20%
• Baseline Scan 20%
• PET Scan 20%
• Occupancy 20%
• Intravenous Injection 20%
• Drug Use 20%
• Image Registration 20%
• Statistical Analysis 20%
• Sedation 20%
• Healthy Adults 20%
• Linear Regression 20%
• High Specific Activity 20%
• Cerebellum 20%
• Allergy 20%
• Third Generation 20%
• Transport Rate 20%
• Pharmacological Effects 20%
• Computational Efficiency 20%
• Spatial Normalization 20%
• Caudate-putamen 20%
• Potential Distribution 20%
• Robust Linear Regression 20%
• Volume Images 20%
• Intra-subject 20%
• Oral Therapeutics 20%
• Operational Equations 20%
• Pixel Distribution 20%
• Therapeutic Dose 20%
• 3-Parameter Model 20%

Neuroscience

• Positron Emission Tomography 100%
• Antihistamines 100%
• Doxepin 100%
• Histamine H1 Receptor 83%
• Fexofenadine 33%
• Benadryl 33%
• Cetirizine 33%
• Diphenhydramine 33%
• Thalamus 16%
• Positron Emission Tomography 16%
• Putamen 16%
• Central Nervous System 16%
• DNA Template 16%
• Cerebellum 16%
• Image Registration 16%
• Side Effect 16%