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Evaluation of analogues of furan-amidines as inhibitors of NQO2
Soraya Alnabulsi
, Buthaina Hussein
, Elham Santina
, Izzeddin Alsalahat
, Manikandan Kadirvel
, Rachael N. Magwaza
, Richard A. Bryce
, Carl H. Schwalbe
, Alex G. Baldwin
, Ilaria Russo
, Ian J. Stratford
, Sally Freeman
Division of Infectious Diseases
Research output
:
Contribution to journal
›
Article
›
peer-review
20
Scopus citations
Overview
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Keyphrases
Amidines
100%
Furan
100%
Quinone Oxidoreductase 2
100%
Oxazole
28%
Methyl
14%
In Cancer
14%
Structure-activity Relationship
14%
IC50 Value
14%
Potent Inhibitor
14%
Plasmodium Falciparum
14%
X-ray Crystallography
14%
Imidazole
14%
Low Activity
14%
Malaria
14%
Cancer Chemotherapy
14%
Molecular Docking
14%
Heterocycles
14%
Thiophene
14%
Molecular Binding
14%
Benzamidine
14%
Non-axisymmetric
14%
1-methylimidazole
14%
Novel Analogues
14%
Furan Ring
14%
Unexpected Product
14%
Amidoxime
14%
Amidine Group
14%
Binding Mode Analysis
14%
Imidates
14%
Docking Mode
14%
N-arylamides
14%
Chemistry
Furan
100%
Quinone
100%
Amidine
100%
Oxazole
25%
Structure-Activity Relationship
12%
IC50
12%
Alkalinity
12%
Imidazole
12%
X-Ray Crystallography
12%
Heterocyclic Compound
12%
Amidoxime
12%
Benzamidine
12%
Imidate
12%
Arylamide
12%
Thiophene
12%
Molecular Docking
12%
Pharmacology, Toxicology and Pharmaceutical Science
Oxidoreductase
100%
Amidinium
100%
Furan
100%
Oxazole
25%
Structure Activity Relationship
12%
Imidazole
12%
IC50
12%
Plasmodium falciparum
12%
Cancer Chemotherapy
12%
Thiophene
12%
Benzamidine
12%