Evaluation of a latex agglutination test for herpes simplex virus

G. A. Storch, C. A. Reed, Z. A. Dalu

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

We evaluated a new commercial latex agglutination test for herpes simplex virus antigen detection (Virogen Herpes Slide Test, Wampole Laboratories, Cranbury, N.J.). In testing of eluates from 100 lesion swabs, mostly from genital sites, the following test parameters were ascertained: sensitivity, 73%; specificity, 89%; positive predictive value, 89%; negative predictive value, 72%. Testing was also performed on 160 supernatants from 153 cell cultures inoculated with clinical samples. In this application, sensitivity and specificity were each 100%, provided supernatants were sampled for testing when the cytopathic effect involved at least 25% of the cell monolayer.

Original languageEnglish
Pages (from-to)787-788
Number of pages2
JournalJournal of clinical microbiology
Volume26
Issue number4
StatePublished - Jan 1 1988

Fingerprint Dive into the research topics of 'Evaluation of a latex agglutination test for herpes simplex virus'. Together they form a unique fingerprint.

Cite this