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Estimation of elastic parameters of ovarian tissue using phase stabilized swept source optical-coherence tomography

  • Sreyankar Nandy
  • , Tianheng Wang
  • , Hassan Salehi
  • , Melinda Sanders
  • , Molly Brewer
  • , Quing Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We have estimated the micro-mechanical properties of ovarian tissue using phase-sensitive swept source optical coherence tomography. Ovary samples were mechanically excited by periodical vibration of an ultrasound transducer. The displacement and strain of the tissues were calculated during loading. Significant difference in strain was observed between the normal and malignant ovary groups, which indicates much softer and heterogeneous tissue structure for malignant ovaries. The initial results show that the phase sensitive swept source optical coherence elastography (OCE) can be an effective tool for characterization of stiffness and other micro-mechanical properties of normal and malignant ovarian tissue.

Original languageEnglish
Title of host publicationOptical Elastography and Tissue Biomechanics II
EditorsKirill V. Larin, David D. Sampson
PublisherSPIE
ISBN (Electronic)9781628414172
DOIs
StatePublished - 2015
EventOptical Elastography and Tissue Biomechanics II - San Francisco, United States
Duration: Feb 7 2015Feb 8 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9327
ISSN (Print)1605-7422

Conference

ConferenceOptical Elastography and Tissue Biomechanics II
Country/TerritoryUnited States
CitySan Francisco
Period02/7/1502/8/15

Keywords

  • Displacement
  • Optical elastography
  • Ovarian tissue
  • Phase sensitive optical coherence tomography
  • Strain

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