TY - GEN
T1 - Estimate of electromotive surface dimension during ventricular fibrillation
AU - Witkowski, Francis X.
AU - Penkoske, Patricia A.
AU - Kavanagh, Katherine M.
N1 - Funding Information:
This work was supported by grants from the Alberta Heritage Foundation for Medical Research and from the Medical Research Council of Canada.
Publisher Copyright:
© 1992 IEEE.
PY - 1992
Y1 - 1992
N2 - The accurate identification of local activation from extracellular recording electrodes attached to the beating heart is critical for the development of a mechanistic understanding of serious cardiac rhythm disturbances in both experimental animals and man. One of the most complex of these rhythm disturbances is ventricular fibrillation, a common cause of sudden cardiac death in man. When using bipolar extracellular recording electrodes to detect local activation, the spatial extent of the upstroke of the action potentials that generate the extracellular waveform determines the optimal interelectrode distances for the bipolar electrodes. This spatial length has been well characterized for normal cardiac conduction at around 1.0 mm on the epicardial surface. We found that for many of the activations occurring during early ventricular fibrillation this length is similarly around 1.0 mm.
AB - The accurate identification of local activation from extracellular recording electrodes attached to the beating heart is critical for the development of a mechanistic understanding of serious cardiac rhythm disturbances in both experimental animals and man. One of the most complex of these rhythm disturbances is ventricular fibrillation, a common cause of sudden cardiac death in man. When using bipolar extracellular recording electrodes to detect local activation, the spatial extent of the upstroke of the action potentials that generate the extracellular waveform determines the optimal interelectrode distances for the bipolar electrodes. This spatial length has been well characterized for normal cardiac conduction at around 1.0 mm on the epicardial surface. We found that for many of the activations occurring during early ventricular fibrillation this length is similarly around 1.0 mm.
UR - http://www.scopus.com/inward/record.url?scp=85024969939&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.1992.5761144
DO - 10.1109/IEMBS.1992.5761144
M3 - Conference contribution
AN - SCOPUS:85024969939
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 631
EP - 632
BT - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 1992
A2 - Coatrieux, Jean Louis
A2 - Morucci, Jean Pierre
A2 - Laxminarayan, Swamy
A2 - Plonsey, Robert
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 1992
Y2 - 29 October 1992 through 1 November 1992
ER -