Abstract

Studies of the human microbiome are progressing rapidly but have largely focused on populations living in high-income countries. With increasing evidence that the microbiome contributes to the pathogenesis of diseases that affect infants, children, and adults in low- and middle-income countries (LMICs), and with profound and rapid ongoing changes occurring in our lifestyles and biosphere, understanding the origins of and developing microbiome-directed therapeutics for treating a number of global health challenges requires the development of programs for studying human microbial ecology in LMICs. Here, we discuss how the establishment of long-term human microbial observatory programs in selected LMICs could provide one timely approach.

Original languageEnglish
Pages (from-to)13-20
Number of pages8
JournalAnnals of the New York Academy of Sciences
Volume1540
Issue number1
DOIs
StatePublished - Oct 2024

Keywords

  • capacity building
  • childhood and maternal malnutrition
  • gut microbiome function and therapeutics
  • low- and middle-income countries
  • microbiome research ethics and regulation

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