Esophageal Manometry in Gastroesophageal Reflux Disease

Michael Mello, C. Prakash Gyawali

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


High-resolution manometry (HRM) allows nuanced evaluation of esophageal motor function, and more accurate evaluation of lower esophageal sphincter (LES) function, in comparison with conventional manometry. Pathophysiologic correlates of gastroesophageal reflux disease (GERD) and esophageal peristaltic performance are well addressed by this technique. HRM may alter the surgical decision by assessment of esophageal peristaltic function and exclusion of esophageal outflow obstruction before antireflux surgery. Provocative testing during HRM may assess esophageal smooth muscle peristaltic reserve and help predict the likelihood of transit symptoms following antireflux surgery. HRM represents a continuously evolving new technology that compliments the evaluation and management of GERD.

Original languageEnglish
Pages (from-to)69-87
Number of pages19
JournalGastroenterology Clinics of North America
Issue number1
StatePublished - Mar 2014


  • Esophageal hypomotility
  • High-resolution manometry
  • Hypotensive lower esophageal sphincter
  • Multiple rapid swallows
  • Preoperative testing


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