@article{48e14af9490542eba09591b6d29415f2,
title = "Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation",
abstract = "Inflammation mediates tissue repair but can be hijacked to promote tumorigenesis. Hoste et al. demonstrate that HMGB1 delays regeneration and drives tumor formation in skin by recruitment and priming of neutrophils. These data indicate that therapies targeting HMGB1 or NET formation might be relevant in chronic and diabetic wound treatment.",
keywords = "HMGB1, TNF, diabetes, epidermolysis bullosa, innate immunity, neutrophil extracellular traps, skin inflammation, tumor microenvironment, wound healing",
author = "Esther Hoste and Christian Mauer{\"o}der and {van Hove}, Lisette and Leen Catrysse and Vikkula, {Hanna Kaisa} and Mozes Sze and Bastiaan Maes and Dyah Karjosukarso and Liesbet Martens and Amanda Gon{\c c}alves and Eef Parthoens and Ria Roelandt and Wim Declercq and Ignacia Fuentes and Francis Palisson and Sergio Gonzalez and Salas-Alanis, {Julio C.} and Louis Boon and Peter Huebener and Mulder, {Klaas Willem} and Kodi Ravichandran and Yvan Saeys and Schwabe, {Robert Felix} and {van Loo}, Geert",
note = "Publisher Copyright: {\textcopyright} 2019 The Author(s)",
year = "2019",
month = nov,
day = "26",
doi = "10.1016/j.celrep.2019.10.104",
language = "English",
volume = "29",
pages = "2689--2701.e4",
journal = "Cell Reports",
issn = "2211-1247",
number = "9",
}