Epilepsy in the nevoid basal-cell carcinoma syndrome (Gorlin syndrome): Report of a case due to a focal neuronal heterotopia

R. E. Hogan; B. Tress; M. F. Gonzales; J. O. King; M. J. Cook

doi:10.1212/WNL.46.2.574

Epilepsy in the nevoid basal-cell carcinoma syndrome (Gorlin syndrome): Report of a case due to a focal neuronal heterotopia

R. E. Hogan, B. Tress, M. F. Gonzales, J. O. King, M. J. Cook

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Abstract

We present a case of uncontrolled temporal lobe epilepsy due to a focal left temporal neuronal heterotopia associated with the nevoid-basal-cell carcinoma syndrome. This is the first pathologically described lesion associated with temporal lobe epilepsy in this syndrome. Because the patient's seizures resolved after a modified left anterior temporal lobectomy, this case illustrates that epilepsy in patients with the nevoid basal-cell carcinoma syndrome is potentially curable and should be investigated appropriately.

Original language	English
Pages (from-to)	574-576
Number of pages	3
Journal	Neurology
Volume	46
Issue number	2
DOIs	https://doi.org/10.1212/WNL.46.2.574
State	Published - Feb 1996

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abstract = "We present a case of uncontrolled temporal lobe epilepsy due to a focal left temporal neuronal heterotopia associated with the nevoid-basal-cell carcinoma syndrome. This is the first pathologically described lesion associated with temporal lobe epilepsy in this syndrome. Because the patient's seizures resolved after a modified left anterior temporal lobectomy, this case illustrates that epilepsy in patients with the nevoid basal-cell carcinoma syndrome is potentially curable and should be investigated appropriately.",

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AB - We present a case of uncontrolled temporal lobe epilepsy due to a focal left temporal neuronal heterotopia associated with the nevoid-basal-cell carcinoma syndrome. This is the first pathologically described lesion associated with temporal lobe epilepsy in this syndrome. Because the patient's seizures resolved after a modified left anterior temporal lobectomy, this case illustrates that epilepsy in patients with the nevoid basal-cell carcinoma syndrome is potentially curable and should be investigated appropriately.

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Epilepsy in the nevoid basal-cell carcinoma syndrome (Gorlin syndrome): Report of a case due to a focal neuronal heterotopia

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