Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer

Keyphrases

• Primary Liver Cancer 100%
• Epigenetic Annotations 100%
• Non-synonymous mutation 100%
• Regulatory Elements 83%
• In Cancer 50%
• Coding mutation 50%
• Binding Site 33%
• Cancer Genome 33%
• Non-coding 33%
• Single nucleotide Variant 33%
• Somatic Single nucleotide Variants 33%
• Mitogen-activated Protein Kinase 16%
• Somatic mutation 16%
• Liver Cancer 16%
• Potential Gains 16%
• Gene mutation 16%
• Protein-coding Genes 16%
• Parsing 16%
• Patient Demographics 16%
• Transcriptional Regulator 16%
• Nonsynonymous 16%
• Biological Consequences 16%
• Publicly Available 16%
• Mechanism of Action 16%
• Epigenome 16%
• Cancer Drivers 16%
• Driver Events 16%
• Promoter mutation 16%
• Mutation Burden 16%
• ErbB Signaling 16%
• Pathway mutation 16%

Biochemistry, Genetics and Molecular Biology

• Regulatory Element 100%
• Single-Nucleotide Polymorphism 80%
• Binding Site 40%
• Promoter Region 40%
• Somatic Mutation 20%
• Epigenome 20%
• MAPK Signaling 20%