TY - JOUR
T1 - Epidemiology of Uveitis in Olmsted County, Minnesota
T2 - A Population-Based Follow-Up Study
AU - Xu, Timothy T.
AU - Reynolds, Margaret M.
AU - Hodge, David O.
AU - Smith, Wendy M.
N1 - Publisher Copyright:
© 2021 Taylor & Francis Group, LLC.
PY - 2023
Y1 - 2023
N2 - Purpose: To update the incidence of uveitis in a Midwestern U.S. county population. Methods: Retrospective population-based cohort study. All Olmsted County, Minnesota residents diagnosed with uveitis from January 1, 2006 to December 31, 2015 were identified via the Rochester Epidemiology Project. Diagnoses were confirmed by a uveitis specialist. Results: There were 371 incident uveitis cases, yielding an overall age- and sex-adjusted incidence rate of 26.9 per 100,000 per year (95% CI: 24.1–29.7). Females accounted for 202 (54.4%) cases, 306 (82.5%) were White, and 299 (80.6%) were anterior uveitis. Highest incidence was observed in patients ≥65 years old. No difference in incidence existed between sexes (p = .17). Incidence rates increased with age for uveitis overall (all anatomic subtypes) (p < .001), anterior uveitis (p < .001), and posterior uveitis (p < .001). Idiopathic uveitis accounted for 168 (45.3%) cases, more frequently diagnosed in females (50.0%) than males (39.6%) (p = .05). Conclusion: Uveitis incidence increased 1.6-fold over a 50-year span in this predominately White U.S. Midwestern county population.
AB - Purpose: To update the incidence of uveitis in a Midwestern U.S. county population. Methods: Retrospective population-based cohort study. All Olmsted County, Minnesota residents diagnosed with uveitis from January 1, 2006 to December 31, 2015 were identified via the Rochester Epidemiology Project. Diagnoses were confirmed by a uveitis specialist. Results: There were 371 incident uveitis cases, yielding an overall age- and sex-adjusted incidence rate of 26.9 per 100,000 per year (95% CI: 24.1–29.7). Females accounted for 202 (54.4%) cases, 306 (82.5%) were White, and 299 (80.6%) were anterior uveitis. Highest incidence was observed in patients ≥65 years old. No difference in incidence existed between sexes (p = .17). Incidence rates increased with age for uveitis overall (all anatomic subtypes) (p < .001), anterior uveitis (p < .001), and posterior uveitis (p < .001). Idiopathic uveitis accounted for 168 (45.3%) cases, more frequently diagnosed in females (50.0%) than males (39.6%) (p = .05). Conclusion: Uveitis incidence increased 1.6-fold over a 50-year span in this predominately White U.S. Midwestern county population.
KW - Uveitis
KW - epidemiology
KW - population-based
UR - http://www.scopus.com/inward/record.url?scp=85119692769&partnerID=8YFLogxK
U2 - 10.1080/09273948.2021.1988113
DO - 10.1080/09273948.2021.1988113
M3 - Article
C2 - 34802369
AN - SCOPUS:85119692769
SN - 0927-3948
VL - 31
SP - 112
EP - 118
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
IS - 1
ER -