TY - JOUR
T1 - Epidemiology of Uveitis in Olmsted County, Minnesota
T2 - A Population-Based Follow-Up Study
AU - Xu, Timothy T.
AU - Reynolds, Margaret M.
AU - Hodge, David O.
AU - Smith, Wendy M.
N1 - Funding Information:
This study was made possible using the resources of the Rochester Epidemiology Project, which is supported by the National Institute on Aging of the National Institutes of Health under Award Number [R01AG034676]. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The funding source had no role in conduct of the research and preparation of the article.
Publisher Copyright:
© 2021 Taylor & Francis Group, LLC.
PY - 2023
Y1 - 2023
N2 - Purpose: To update the incidence of uveitis in a Midwestern U.S. county population. Methods: Retrospective population-based cohort study. All Olmsted County, Minnesota residents diagnosed with uveitis from January 1, 2006 to December 31, 2015 were identified via the Rochester Epidemiology Project. Diagnoses were confirmed by a uveitis specialist. Results: There were 371 incident uveitis cases, yielding an overall age- and sex-adjusted incidence rate of 26.9 per 100,000 per year (95% CI: 24.1–29.7). Females accounted for 202 (54.4%) cases, 306 (82.5%) were White, and 299 (80.6%) were anterior uveitis. Highest incidence was observed in patients ≥65 years old. No difference in incidence existed between sexes (p = .17). Incidence rates increased with age for uveitis overall (all anatomic subtypes) (p < .001), anterior uveitis (p < .001), and posterior uveitis (p < .001). Idiopathic uveitis accounted for 168 (45.3%) cases, more frequently diagnosed in females (50.0%) than males (39.6%) (p = .05). Conclusion: Uveitis incidence increased 1.6-fold over a 50-year span in this predominately White U.S. Midwestern county population.
AB - Purpose: To update the incidence of uveitis in a Midwestern U.S. county population. Methods: Retrospective population-based cohort study. All Olmsted County, Minnesota residents diagnosed with uveitis from January 1, 2006 to December 31, 2015 were identified via the Rochester Epidemiology Project. Diagnoses were confirmed by a uveitis specialist. Results: There were 371 incident uveitis cases, yielding an overall age- and sex-adjusted incidence rate of 26.9 per 100,000 per year (95% CI: 24.1–29.7). Females accounted for 202 (54.4%) cases, 306 (82.5%) were White, and 299 (80.6%) were anterior uveitis. Highest incidence was observed in patients ≥65 years old. No difference in incidence existed between sexes (p = .17). Incidence rates increased with age for uveitis overall (all anatomic subtypes) (p < .001), anterior uveitis (p < .001), and posterior uveitis (p < .001). Idiopathic uveitis accounted for 168 (45.3%) cases, more frequently diagnosed in females (50.0%) than males (39.6%) (p = .05). Conclusion: Uveitis incidence increased 1.6-fold over a 50-year span in this predominately White U.S. Midwestern county population.
KW - Uveitis
KW - epidemiology
KW - population-based
UR - http://www.scopus.com/inward/record.url?scp=85119692769&partnerID=8YFLogxK
U2 - 10.1080/09273948.2021.1988113
DO - 10.1080/09273948.2021.1988113
M3 - Article
C2 - 34802369
AN - SCOPUS:85119692769
SN - 0927-3948
VL - 31
SP - 112
EP - 118
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
IS - 1
ER -