TY - JOUR
T1 - Epicardial ablation performance of a novel radiofrequency device on the beating heart in pigs
AU - Watanabe, Yoshiyuki
AU - Weimar, Timo
AU - Kazui, Toshinobu
AU - Lee, Urvi
AU - Schuessler, Richard B.
AU - Damiano, Ralph J.
N1 - Funding Information:
This study was supported in part by National Institutes of Health grants 5R01 HL032257, R01 HL085113, and T32 HL07776. Drs Schuessler and Damiano receive research grants and equipment from AtriCure, Inc. Dr Damiano receives consultant fees from AtriCure and Medtronic.
PY - 2014/2
Y1 - 2014/2
N2 - Purpose Only bipolar clamps create reliable transmural lesions on the beating heart. This study evaluated the performance of a new radiofrequency (RF) device on the beating heart in an acute porcine model. Description Six domestic pigs were ablated with a novel bipolar RF linear device on the beating heart (ablation time of 40 s, 3 each on right and left atria and 1 each on superior and inferior vena cavae). The heart was stained with 2, 3, 5-triphenyl- tetrazolium chloride, and each lesion was cross-sectioned for lesion depth and transmurality. Evaluation Transmurality was documented in 89% of the cross-sections. Sixty-three percent of lesions were transmural along the entire lesion length. Overall, 85% of the nontransmural cross-sections were located on the right atrium, and half of the nontransmural sections were in the superior or inferior vena cavae lesions. Conclusions This novel device was able to create transmural lesions on the beating heart, more effectively in the left atrium than in the right atrium.
AB - Purpose Only bipolar clamps create reliable transmural lesions on the beating heart. This study evaluated the performance of a new radiofrequency (RF) device on the beating heart in an acute porcine model. Description Six domestic pigs were ablated with a novel bipolar RF linear device on the beating heart (ablation time of 40 s, 3 each on right and left atria and 1 each on superior and inferior vena cavae). The heart was stained with 2, 3, 5-triphenyl- tetrazolium chloride, and each lesion was cross-sectioned for lesion depth and transmurality. Evaluation Transmurality was documented in 89% of the cross-sections. Sixty-three percent of lesions were transmural along the entire lesion length. Overall, 85% of the nontransmural cross-sections were located on the right atrium, and half of the nontransmural sections were in the superior or inferior vena cavae lesions. Conclusions This novel device was able to create transmural lesions on the beating heart, more effectively in the left atrium than in the right atrium.
KW - 24
KW - CTSNet classification
UR - http://www.scopus.com/inward/record.url?scp=84893400126&partnerID=8YFLogxK
U2 - 10.1016/j.athoracsur.2013.10.036
DO - 10.1016/j.athoracsur.2013.10.036
M3 - Article
C2 - 24484804
AN - SCOPUS:84893400126
SN - 0003-4975
VL - 97
SP - 673
EP - 678
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 2
ER -