EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission

Jasmin I. Maier, Manuel Rogg, Martin Helmstädter, Alena Sammarco, Oliver Schilling, Benedikt Sabass, Jeffrey H. Miner, Jörn Dengjel, Gerd Walz, Martin Werner, Tobias B. Huber, Christoph Schell

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Maier et al. describe an EPB41L5-controlled mechanism for how force transmission by integrin-based adhesion complexes (IACs) controls the structural integrity and function of the glomerular basement membrane (GBM).

Original languageEnglish
Article number108883
JournalCell Reports
Volume34
Issue number12
DOIs
StatePublished - Mar 23 2021

Keywords

  • ECM
  • EPB41L5
  • GBM
  • IAC
  • PDLIM5
  • extracellular matrix
  • focal adhesion
  • glomerular basement membrane
  • matrisome
  • podocyte

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