Eosinophils are recruited in response to chitin exposure and enhance Th2-mediated immune pathology in aspergillus Fumigatus infection

Agriculture & Biology

• Aspergillus fumigatus 86%
• eosinophils 82%
• chemokine CCL22 80%
• chemokine CCL11 78%
• chitin 76%
• lungs 58%
• morbidity 58%
• eosinophilia 51%
• immune response 46%
• mice 42%
• infection 39%
• conidia 35%
• interleukin-4 22%
• host-pathogen relationships 22%
• interferon-gamma 21%
• cell wall components 20%
• chitinase 19%
• neutrophils 17%
• T-lymphocytes 16%
• therapeutics 14%
• fluids 13%
• germination 13%
• secretion 13%
• fungi 11%

Medicine & Life Sciences

• Chitin 100%
• Aspergillus fumigatus 91%
• Aspergillosis 88%
• Eosinophils 72%
• Chemokine CCL11 60%
• Fungal Spores 51%
• Pathology 47%
• Eosinophilia 40%
• Lung 39%
• Morbidity 32%
• Chemokine CCL22 29%
• Chitinases 26%
• Germination 26%
• Host-Pathogen Interactions 24%
• Bronchoalveolar Lavage Fluid 20%
• Cellular Structures 19%
• Cell Wall 18%
• Interleukin-4 17%
• Fungi 16%
• Interferon-gamma 16%
• Neutrophils 14%
• T-Lymphocytes 11%
• Mortality 9%
• Infections 8%