Eosinophilic Pancreatitis: A Rare Cause of Recurrent Acute Pancreatitis

Jennifer Reppucci, Michael Chang, Steven Hughes, Xiuli Liu

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7 Scopus citations


Eosinophilic pancreatitis is a rare form of recurrent acute pancreatitis that demonstrates distinct histologic features, including diffuse, periductal, acinar, and septal inflammatory infiltrates comprised of a pure or predominant population of eosinophils, eosinophilic phlebitis and arteritis, and localized eosinophilic infiltrates with pseudocyst formation. It is associated with elevated serum immunoglobulin E levels, an elevated eosinophil count with systemic manifestations, and eosinophilic infiltrates in other organs of the gastrointestinal tract. We present a case of eosinophilic pancreatitis in a 44-year-old man who was diagnosed after pancreatic resection for recurrent bouts of acute pancreatitis. While the gross and histologic evaluations matched other reported cases of eosinophilic pancreatitis, our patient had only minimal peripheral eosinophilia, no reported history of symptoms related to elevated eosinophilia or immunoglobulin E, and only mild eosinophilic infiltrates in his gallbladder.

Original languageEnglish
Pages (from-to)120-126
Number of pages7
JournalCase Reports in Gastroenterology
Issue number1
StatePublished - Jan 27 2017


  • Eosinophilic pancreatitis
  • Eosinophils
  • Recurrent acute pancreatitis


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