@article{3726cf7afa1c415d8a89e2017b5d686b,
title = "Eosinophilic granuloma of the sacrum treated with radiation therapy: A case report",
abstract = "Background Context Eosinophilic granulomas (EGs) of the sacrum have been reported in fewer than 10 patients. Treatment algorithms for these tumors remain poorly defined; there are no reports of treating solitary sacral EG with radiation therapy (RT). Purpose This study aimed to describe the presentation, treatment, and outcome of sacral EG in an adult patient with intractable pain and radiculopathy, treated in a novel fashion with RT. Study Design/Setting The study design was a case report from a tertiary cancer referral center. Methods Patient records, imaging, and pathology were reviewed. Results A 35-year-old man received 20 Gy of radiation to his S1 EG lesion. He subsequently developed vertebra plana of S1 causing symptomatic L5-S1 stenosis, but 15 months after RT treatment was free of pain or tumor recurrence. Conclusion Radiation therapy is an effective treatment option for sacral EG causing severe axial pain and neural impingement.",
keywords = "Benign bone tumor, Eosinophilic granuloma, Langerhans cell histiocytosis, Radiation therapy, Sacrum, Spine tumor",
author = "Bumpass, {David B.} and Andrew Park and Hill, {Kirk T.} and Jiayi Huang and Friedman, {Michael V.} and Zebala, {Lukas P.}",
note = "Funding Information: Author disclosures: DBB: Consulting: Gerson-Lehrman Group (A, Paid directly to author), Doximity (A, Paid directly to author), outside the submitted work; Grants: North American Spine Society (D, Paid directly to institution/employer), outside the submitted work. AP: Nothing to disclose. KTH: Nothing to disclose. JH: Nothing to disclose. MVF: Nothing to disclose. LPZ: Consulting: K2M, Inc. (none), Ulrich Medical USA (B, Paid directly to author), outside the submitted work; Speaking and/or Teaching Arrangements: Broadwater (B, Paid directly to author), DePuy (B, Paid directly to author), K2M, Inc. (B, Paid directly to author), Honoraria outside the submitted work; Trips/Travel: Scoliosis Research Society (Reimbursement for travel accommodations only, Paid directly to author), Synthes Spine (Reimbursement for travel accommodations only, Paid directly to author), outside the submitted work; Fellowship Support: AO Spine (Institutional fellowship support, Paid directly to institution/employer), outside the submitted work. In addition, Dr Zebala reports Education Grant for Cadaver Course from DePuy, Grant #204502 (Loaned instrumentation, no monetary value) in 2014. Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",
year = "2016",
month = jan,
day = "1",
doi = "10.1016/j.spinee.2015.09.022",
language = "English",
volume = "16",
pages = "e53--e57",
journal = "Spine Journal",
issn = "1529-9430",
number = "1",
}