Abstract
The various techniques used for enzyme redesigning were discussed. The process enzyme redesign addresses questions of catalysis and ligand recognition and provides a basis for the applied use of engineered enzymes. The results show that modification of stereochemical outcome of a reaction has practical benefits as many enzymes serve as chiral catalysts for synthetic purposes in the chemical and pharmaceutical industry.
Original language | English |
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Pages (from-to) | 3027-3046 |
Number of pages | 20 |
Journal | Chemical Reviews |
Volume | 101 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2001 |