Entropic compression of interacting DNA loops

Sumithra Sankararaman, John F. Marko

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

We solve a model for the equilibrium folding of DNA via the formation of randomly placed (nonspecific) loops. We find that the loop rearrangement entropy drives a significant reduction in loop size as more loops form. The reduction of the most probable loop size occurs over a wide range of forces and is enhanced by interloop cooperativity, indicating that it should be observable in single DNA experiments.

Original languageEnglish
Article number078104
JournalPhysical Review Letters
Volume95
Issue number7
DOIs
StatePublished - Aug 12 2005
Externally publishedYes

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