Entropic compression of interacting DNA loops

Sumithra Sankararaman, John F. Marko

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


We solve a model for the equilibrium folding of DNA via the formation of randomly placed (nonspecific) loops. We find that the loop rearrangement entropy drives a significant reduction in loop size as more loops form. The reduction of the most probable loop size occurs over a wide range of forces and is enhanced by interloop cooperativity, indicating that it should be observable in single DNA experiments.

Original languageEnglish
Article number078104
JournalPhysical Review Letters
Issue number7
StatePublished - Aug 12 2005


Dive into the research topics of 'Entropic compression of interacting DNA loops'. Together they form a unique fingerprint.

Cite this