Abstract
We solve a model for the equilibrium folding of DNA via the formation of randomly placed (nonspecific) loops. We find that the loop rearrangement entropy drives a significant reduction in loop size as more loops form. The reduction of the most probable loop size occurs over a wide range of forces and is enhanced by interloop cooperativity, indicating that it should be observable in single DNA experiments.
Original language | English |
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Article number | 078104 |
Journal | Physical Review Letters |
Volume | 95 |
Issue number | 7 |
DOIs | |
State | Published - Aug 12 2005 |