Abstract
A recent study by Ascic et al. demonstrates that in situ reprogramming of tumor cells into conventional dendritic cell (cDC)-like cells using viral-PIB transcription factors creates an immunogenic tumor microenvironment with T cell recruitment and activation. The study highlights the potential of tumor-specific cancer immunotherapy using in vivo reprogrammed cDCs.
Original language | English |
---|---|
Pages (from-to) | 934-936 |
Number of pages | 3 |
Journal | Trends in Immunology |
Volume | 45 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2024 |