Abstract

A recent study by Ascic et al. demonstrates that in situ reprogramming of tumor cells into conventional dendritic cell (cDC)-like cells using viral-PIB transcription factors creates an immunogenic tumor microenvironment with T cell recruitment and activation. The study highlights the potential of tumor-specific cancer immunotherapy using in vivo reprogrammed cDCs.

Original languageEnglish
Pages (from-to)934-936
Number of pages3
JournalTrends in Immunology
Volume45
Issue number12
DOIs
StatePublished - Dec 2024

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