Enhancing recovery in coronary heart disease (ENRICHD) study intervention: Rationale and design

L. Berkman; A. Jaffe; R. Carney; S. Czajkowski; P. Kaufman; J. A. Blumenthal; P. Arias; M. Babyak; T. Baldewicz; J. Barefoot; J. Bennett; R. Carels; B. Crenshaw; S. Curtis; L. Davis; K. Fath; L. Forman; A. Hassett; S. B. Hegde; S. H. Herman; A. Hinderliter; P. Khatri; W. Kraus; R. Krishnan; S. Levenberg; D. Mark; P. Marz; R. McCarthy; G. Miller; J. Norten; C. O'Connor; J. Puma; L. Rutt; W. Sessions; I. Siegler; L. Watkins; R. Waugh; R. Williams; A. Wilson; B. G. Zakhary; L. H. Powell; J. E. Calvin; D. C. Clark; S. Creech; D. Downs; C. Eaton; W. J. Elliott; L. Kassem; A. Luten; C. M. De Leon; W. S. Miles; R. Munoz-Dunbar; P. Pfenninger; C. R. Pitula; S. Szeplakay; J. Zajecka; J. Zander; R. F. Debusk; L. Balenesi; A. Casteneda; A. Deeter; S. Duenke; L. F. Forseth; E. S. Froelicher; R. Hanna; H. Kaiser; S. Lamb; S. Madan; M. Marnell; N. H. Miller; K. Parker; D. Strachowski; B. Taylor; C. E. Thoresen; J. Raczynski; B. Adams; S. Allison; M. Bandy; J. Barton; L. Bates; V. Bittner; M. Cole; C. E. Cornell; V. DiLillo; J. Dolce; J. Gilliland; S. Jordan; J. Markovitz; D. Mason; J. Shuster; P. White; S. Winders; N. Schneiderman; M. Gellman; G. Ironson; K. Kilbourn; M. E. Manrique-Reichard; J. R. McCalla; T. Mellman

Enhancing recovery in coronary heart disease (ENRICHD) study intervention: Rationale and design

L. Berkman
, A. Jaffe
, R. Carney
, S. Czajkowski
, P. Kaufman
, J. A. Blumenthal
, P. Arias
, M. Babyak
, T. Baldewicz
, J. Barefoot
, J. Bennett
, R. Carels
, B. Crenshaw
, S. Curtis
, L. Davis
, K. Fath
, L. Forman
, A. Hassett
, S. B. Hegde
, S. H. Herman

A. Hinderliter, P. Khatri, W. Kraus, R. Krishnan, S. Levenberg, D. Mark, P. Marz, R. McCarthy, G. Miller, J. Norten, C. O'Connor, J. Puma, L. Rutt, W. Sessions, I. Siegler, L. Watkins, R. Waugh, R. Williams, A. Wilson, B. G. Zakhary, L. H. Powell, J. E. Calvin, D. C. Clark, S. Creech, D. Downs, C. Eaton, W. J. Elliott, L. Kassem, A. Luten, C. M. De Leon, W. S. Miles, R. Munoz-Dunbar, P. Pfenninger, C. R. Pitula, S. Szeplakay, J. Zajecka, J. Zander, R. F. Debusk, L. Balenesi, A. Casteneda, A. Deeter, S. Duenke, L. F. Forseth, E. S. Froelicher, R. Hanna, H. Kaiser, S. Lamb, S. Madan, M. Marnell, N. H. Miller, K. Parker, D. Strachowski, B. Taylor, C. E. Thoresen, J. Raczynski, B. Adams, S. Allison, M. Bandy, J. Barton, L. Bates, V. Bittner, M. Cole, C. E. Cornell, V. DiLillo, J. Dolce, J. Gilliland, S. Jordan, J. Markovitz, D. Mason, J. Shuster, P. White, S. Winders, N. Schneiderman, M. Gellman, G. Ironson, K. Kilbourn, M. E. Manrique-Reichard, J. R. McCalla, T. Mellman

Research output: Contribution to journal › Article › peer-review

160 Scopus citations

Abstract

Objective: Depression and low social support are risk factors for medical morbidity and mortality after acute MI. The ENRICHD study is a multicenter, randomized, controlled clinical trial of a cognitive-behavioral treatment for depression and low social support in post-MI patients. A total of 2481 patients were recruited (26% with low social support, 39% with depression, and 34% with low social support and depression). Our objective is to describe the rationale, design, and delivery of the ENRICHD intervention. Methods: Key features of the intervention include the integration of cognitive-behavioral and social learning approaches to the treatment of depression and a diverse set of problems that can contribute to low social support; rapid initiation of treatment after MI; a combination of individual and group modalities; adjunctive pharmacotherapy for severe or intractable depression; training, certification, and supervision of therapists; and quality assurance procedures. Results: The trial's psychosocial and medical outcomes will be presented in future reports. Conclusions: The ENRICHD protocol targets two complex psychosocial risk factors with a multifaceted intervention, which is delivered in an individualized manner to accommodate a demographically, medically, and psychiatrically diverse patient population. Additional research will be needed to identify optimal matches between patient characteristics and specific components of the intervention.

Original language	English
Pages (from-to)	747-755
Number of pages	9
Journal	Psychosomatic Medicine
Volume	63
Issue number	5
State	Published - 2001

Keywords

Clinical trials
Coronary heart disease
Depression
Myocardial infarction
Social support

Cite this

Berkman, L., Jaffe, A., Carney, R., Czajkowski, S., Kaufman, P., Blumenthal, J. A., Arias, P., Babyak, M., Baldewicz, T., Barefoot, J., Bennett, J., Carels, R., Crenshaw, B., Curtis, S., Davis, L., Fath, K., Forman, L., Hassett, A., Hegde, S. B., ... Mellman, T. (2001). Enhancing recovery in coronary heart disease (ENRICHD) study intervention: Rationale and design. Psychosomatic Medicine, 63(5), 747-755.

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title = "Enhancing recovery in coronary heart disease (ENRICHD) study intervention: Rationale and design",

abstract = "Objective: Depression and low social support are risk factors for medical morbidity and mortality after acute MI. The ENRICHD study is a multicenter, randomized, controlled clinical trial of a cognitive-behavioral treatment for depression and low social support in post-MI patients. A total of 2481 patients were recruited (26\% with low social support, 39\% with depression, and 34\% with low social support and depression). Our objective is to describe the rationale, design, and delivery of the ENRICHD intervention. Methods: Key features of the intervention include the integration of cognitive-behavioral and social learning approaches to the treatment of depression and a diverse set of problems that can contribute to low social support; rapid initiation of treatment after MI; a combination of individual and group modalities; adjunctive pharmacotherapy for severe or intractable depression; training, certification, and supervision of therapists; and quality assurance procedures. Results: The trial's psychosocial and medical outcomes will be presented in future reports. Conclusions: The ENRICHD protocol targets two complex psychosocial risk factors with a multifaceted intervention, which is delivered in an individualized manner to accommodate a demographically, medically, and psychiatrically diverse patient population. Additional research will be needed to identify optimal matches between patient characteristics and specific components of the intervention.",

keywords = "Clinical trials, Coronary heart disease, Depression, Myocardial infarction, Social support",

author = "L. Berkman and A. Jaffe and R. Carney and S. Czajkowski and P. Kaufman and Blumenthal, \{J. A.\} and P. Arias and M. Babyak and T. Baldewicz and J. Barefoot and J. Bennett and R. Carels and B. Crenshaw and S. Curtis and L. Davis and K. Fath and L. Forman and A. Hassett and Hegde, \{S. B.\} and Herman, \{S. H.\} and A. Hinderliter and P. Khatri and W. Kraus and R. Krishnan and S. Levenberg and D. Mark and P. Marz and R. McCarthy and G. Miller and J. Norten and C. O'Connor and J. Puma and L. Rutt and W. Sessions and I. Siegler and L. Watkins and R. Waugh and R. Williams and A. Wilson and Zakhary, \{B. G.\} and Powell, \{L. H.\} and Calvin, \{J. E.\} and Clark, \{D. C.\} and S. Creech and D. Downs and C. Eaton and Elliott, \{W. J.\} and L. Kassem and A. Luten and \{De Leon\}, \{C. M.\} and Miles, \{W. S.\} and R. Munoz-Dunbar and P. Pfenninger and Pitula, \{C. R.\} and S. Szeplakay and J. Zajecka and J. Zander and Debusk, \{R. F.\} and L. Balenesi and A. Casteneda and A. Deeter and S. Duenke and Forseth, \{L. F.\} and Froelicher, \{E. S.\} and R. Hanna and H. Kaiser and S. Lamb and S. Madan and M. Marnell and Miller, \{N. H.\} and K. Parker and D. Strachowski and B. Taylor and Thoresen, \{C. E.\} and J. Raczynski and B. Adams and S. Allison and M. Bandy and J. Barton and L. Bates and V. Bittner and M. Cole and Cornell, \{C. E.\} and V. DiLillo and J. Dolce and J. Gilliland and S. Jordan and J. Markovitz and D. Mason and J. Shuster and P. White and S. Winders and N. Schneiderman and M. Gellman and G. Ironson and K. Kilbourn and Manrique-Reichard, \{M. E.\} and McCalla, \{J. R.\} and T. Mellman",

year = "2001",

language = "English",

volume = "63",

pages = "747--755",

journal = "Psychosomatic Medicine",

issn = "0033-3174",

number = "5",

}

Berkman, L, Jaffe, A, Carney, R, Czajkowski, S, Kaufman, P, Blumenthal, JA, Arias, P, Babyak, M, Baldewicz, T, Barefoot, J, Bennett, J, Carels, R, Crenshaw, B, Curtis, S, Davis, L, Fath, K, Forman, L, Hassett, A, Hegde, SB, Herman, SH, Hinderliter, A, Khatri, P, Kraus, W, Krishnan, R, Levenberg, S, Mark, D, Marz, P, McCarthy, R, Miller, G, Norten, J, O'Connor, C, Puma, J, Rutt, L, Sessions, W, Siegler, I, Watkins, L, Waugh, R, Williams, R, Wilson, A, Zakhary, BG, Powell, LH, Calvin, JE, Clark, DC, Creech, S, Downs, D, Eaton, C, Elliott, WJ, Kassem, L, Luten, A, De Leon, CM, Miles, WS, Munoz-Dunbar, R, Pfenninger, P, Pitula, CR, Szeplakay, S, Zajecka, J, Zander, J, Debusk, RF, Balenesi, L, Casteneda, A, Deeter, A, Duenke, S, Forseth, LF, Froelicher, ES, Hanna, R, Kaiser, H, Lamb, S, Madan, S, Marnell, M, Miller, NH, Parker, K, Strachowski, D, Taylor, B, Thoresen, CE, Raczynski, J, Adams, B, Allison, S, Bandy, M, Barton, J, Bates, L, Bittner, V, Cole, M, Cornell, CE, DiLillo, V, Dolce, J, Gilliland, J, Jordan, S, Markovitz, J, Mason, D, Shuster, J, White, P, Winders, S, Schneiderman, N, Gellman, M, Ironson, G, Kilbourn, K, Manrique-Reichard, ME, McCalla, JR & Mellman, T 2001, 'Enhancing recovery in coronary heart disease (ENRICHD) study intervention: Rationale and design', Psychosomatic Medicine, vol. 63, no. 5, pp. 747-755.

TY - JOUR

T1 - Enhancing recovery in coronary heart disease (ENRICHD) study intervention

T2 - Rationale and design

AU - Berkman, L.

AU - Jaffe, A.

AU - Carney, R.

AU - Czajkowski, S.

AU - Kaufman, P.

AU - Blumenthal, J. A.

AU - Arias, P.

AU - Babyak, M.

AU - Baldewicz, T.

AU - Barefoot, J.

AU - Bennett, J.

AU - Carels, R.

AU - Crenshaw, B.

AU - Curtis, S.

AU - Davis, L.

AU - Fath, K.

AU - Forman, L.

AU - Hassett, A.

AU - Hegde, S. B.

AU - Herman, S. H.

AU - Hinderliter, A.

AU - Khatri, P.

AU - Kraus, W.

AU - Krishnan, R.

AU - Levenberg, S.

AU - Mark, D.

AU - Marz, P.

AU - McCarthy, R.

AU - Miller, G.

AU - Norten, J.

AU - O'Connor, C.

AU - Puma, J.

AU - Rutt, L.

AU - Sessions, W.

AU - Siegler, I.

AU - Watkins, L.

AU - Waugh, R.

AU - Williams, R.

AU - Wilson, A.

AU - Zakhary, B. G.

AU - Powell, L. H.

AU - Calvin, J. E.

AU - Clark, D. C.

AU - Creech, S.

AU - Downs, D.

AU - Eaton, C.

AU - Elliott, W. J.

AU - Kassem, L.

AU - Luten, A.

AU - De Leon, C. M.

AU - Miles, W. S.

AU - Munoz-Dunbar, R.

AU - Pfenninger, P.

AU - Pitula, C. R.

AU - Szeplakay, S.

AU - Zajecka, J.

AU - Zander, J.

AU - Debusk, R. F.

AU - Balenesi, L.

AU - Casteneda, A.

AU - Deeter, A.

AU - Duenke, S.

AU - Forseth, L. F.

AU - Froelicher, E. S.

AU - Hanna, R.

AU - Kaiser, H.

AU - Lamb, S.

AU - Madan, S.

AU - Marnell, M.

AU - Miller, N. H.

AU - Parker, K.

AU - Strachowski, D.

AU - Taylor, B.

AU - Thoresen, C. E.

AU - Raczynski, J.

AU - Adams, B.

AU - Allison, S.

AU - Bandy, M.

AU - Barton, J.

AU - Bates, L.

AU - Bittner, V.

AU - Cole, M.

AU - Cornell, C. E.

AU - DiLillo, V.

AU - Dolce, J.

AU - Gilliland, J.

AU - Jordan, S.

AU - Markovitz, J.

AU - Mason, D.

AU - Shuster, J.

AU - White, P.

AU - Winders, S.

AU - Schneiderman, N.

AU - Gellman, M.

AU - Ironson, G.

AU - Kilbourn, K.

AU - Manrique-Reichard, M. E.

AU - McCalla, J. R.

AU - Mellman, T.

PY - 2001

Y1 - 2001

N2 - Objective: Depression and low social support are risk factors for medical morbidity and mortality after acute MI. The ENRICHD study is a multicenter, randomized, controlled clinical trial of a cognitive-behavioral treatment for depression and low social support in post-MI patients. A total of 2481 patients were recruited (26% with low social support, 39% with depression, and 34% with low social support and depression). Our objective is to describe the rationale, design, and delivery of the ENRICHD intervention. Methods: Key features of the intervention include the integration of cognitive-behavioral and social learning approaches to the treatment of depression and a diverse set of problems that can contribute to low social support; rapid initiation of treatment after MI; a combination of individual and group modalities; adjunctive pharmacotherapy for severe or intractable depression; training, certification, and supervision of therapists; and quality assurance procedures. Results: The trial's psychosocial and medical outcomes will be presented in future reports. Conclusions: The ENRICHD protocol targets two complex psychosocial risk factors with a multifaceted intervention, which is delivered in an individualized manner to accommodate a demographically, medically, and psychiatrically diverse patient population. Additional research will be needed to identify optimal matches between patient characteristics and specific components of the intervention.

AB - Objective: Depression and low social support are risk factors for medical morbidity and mortality after acute MI. The ENRICHD study is a multicenter, randomized, controlled clinical trial of a cognitive-behavioral treatment for depression and low social support in post-MI patients. A total of 2481 patients were recruited (26% with low social support, 39% with depression, and 34% with low social support and depression). Our objective is to describe the rationale, design, and delivery of the ENRICHD intervention. Methods: Key features of the intervention include the integration of cognitive-behavioral and social learning approaches to the treatment of depression and a diverse set of problems that can contribute to low social support; rapid initiation of treatment after MI; a combination of individual and group modalities; adjunctive pharmacotherapy for severe or intractable depression; training, certification, and supervision of therapists; and quality assurance procedures. Results: The trial's psychosocial and medical outcomes will be presented in future reports. Conclusions: The ENRICHD protocol targets two complex psychosocial risk factors with a multifaceted intervention, which is delivered in an individualized manner to accommodate a demographically, medically, and psychiatrically diverse patient population. Additional research will be needed to identify optimal matches between patient characteristics and specific components of the intervention.

KW - Clinical trials

KW - Coronary heart disease

KW - Depression

KW - Myocardial infarction

KW - Social support

UR - https://www.scopus.com/pages/publications/0034807282

M3 - Article

C2 - 11573023

AN - SCOPUS:0034807282

SN - 0033-3174

VL - 63

SP - 747

EP - 755

JO - Psychosomatic Medicine

JF - Psychosomatic Medicine

IS - 5

ER -

Enhancing recovery in coronary heart disease (ENRICHD) study intervention: Rationale and design

Abstract

Keywords

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